OBJECTIVE The aim of this study was to analyze the influence of autoantibodies against spermatozoa present in the semen on the outcome of in vitro fertilization with intracytoplasmic sperm injection (ICSI). MATERIALS AND METHODS We performed a retrospective analysis of clinical and laboratorial data from a six year-period ICSI cycles. Screening for the presence of ASA in the semen, by using t...

BACKGROUND Semenogelins (SEMGs) are major components of human seminal vesicle secretions. Due to SEMG's sperm-motility inhibitor, a significant negative correlation between sperm motility and the proportion of SEMG-bound spermatozoa (SEMG+) was found in asthenozoospermic patients. SEMGs also show intrinsic inhibitory capability for sperm capacitation; however, studies on actual clinical specime...

Opioid peptides have been reported to have important functions in human reproduction. Indeed, very high concentrations of enkephalins and their degrading enzymes have been reported in human semen. In the present paper, we compare the activity of two enkephalin-degrading enzymes, aminopeptidase N and neutral endopeptidase 24.11, in different fractions of semen from normozoospermic, fertile men a...

Fucose, the monosaccharide frequent in N- and O-glycans, is a part of Lewis-type antigens that are known to mediate direct sperm binding to the zona pellucida. Such interaction was found to be inhibited in vitroby fucose-containing oligo- and polysaccharides, as well as neoglycoproteins. The objective of this study was to screen seminal plasma proteins of infertile/subfertile men for the conten...

Aim: Infertility is a global problem affecting both males and females. It condition with psychological, economic, medical implications resulting in trauma stress, particularly society where there strong emphasis on childbearing. The study therefore aims to investigate the pattern of some sperm proteins, anti-oxidants, prostate-specific antigen seminal plasma infertile cell deformities.
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mega-3 fatty acids found in some foods have a wide-range of health benefits. The omega-3 supplementation results in higher antioxidant activity in human seminal fluid and enhanced sperm count, sperm motility, and sperm morphology. Considerable number of infertile men with idiopathic oligoasthenoteratozoospermia might be benefit from omega-3 fatty acids administration. Infertility caused by idio...

To evaluate the best method for sperm separation in high DNA fragmentation index (DFI) samples. A prospective randomised study was conducted from 1st January 2019 to 2021. Three hundred patients were by computer generated list and divided into 3 groups. Group (n=100) , which processed microfluidic sorter (MFSS) while group B (n=100), selected Physiological Intracytoplasmic Sperm Injection (PICS...