نتایج جستجو برای: atherosclerotic lesions

تعداد نتایج: 186228  

Journal: :The Journal of Japan Atherosclerosis Society 1989

Journal: :Arteriosclerosis, thrombosis, and vascular biology 1999
T Häkkinen J S Luoma M O Hiltunen C H Macphee K J Milliner L Patel S Q Rice D G Tew K Karkola S Ylä-Herttuala

We studied the expression of lipoprotein-associated phospholipase A(2) (Lp-PLA(2)), an enzyme capable of hydrolyzing platelet-activating factor (PAF), PAF-like phospholipids, and polar-modified phosphatidylcholines, in human and rabbit atherosclerotic lesions. Oxidative modification of low-density lipoprotein, which plays an important role in atherogenesis, generates biologically active PAF-lik...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2003
Marisa Benagiano Annalisa Azzurri Alessandra Ciervo Amedeo Amedei Carlo Tamburini Mauro Ferrari John L Telford Cosima T Baldari Sergio Romagnani Antonio Cassone Mario M D'Elios Gianfranco Del Prete

Atherosclerotic lesions are infiltrated by macrophages and T lymphocytes, potentially reactive to pathogens. We studied in vivo activated T lymphocytes that infiltrate atherosclerotic plaques of Helicobacter pylori-infected patients with or without anti-Chlamydia pneumoniae antibodies. In all atherosclerotic lesions, T helper type 1 (Th1) cells were predominant. C. pneumoniae-specific T cells w...

Journal: :Circulation research 2012
Oliver Soehnlein

Because of their rare detection in atherosclerotic lesions, the involvement of neutrophils in the pathophysiology of atherosclerosis has been largely denied. However, over the past couple of years, studies have provided convincing evidence for the presence of neutrophils in atherosclerotic plaques and further revealed the causal contribution of neutrophils during various stages of atheroscleros...

2014
Lian-Xi Li Xing Wu Jun-Xi Lu Yin-Fang Tu Li-Bo Yu Mei-Fang Li Wei-Xing Zhang Jia-An Zhu Guo-Yue Yuan Yu-Qian Bao Wei-Ping Jia

AIMS/INTRODUCTION To compare carotid and lower limb atherosclerotic lesions, and examine if carotid atherosclerotic lesions are in line with lower limb atherosclerotic lesions, and can reflect generalized atherosclerosis in inpatients with type 2 diabetes. MATERIALS AND METHODS This was an observational study carried out in 867 Chinese inpatients with type 2 diabetes, including 573 previously...

Journal: :Circulation 2013
Tin Kyaw Amy Winship Christopher Tay Peter Kanellakis Hamid Hosseini Anh Cao Priscilla Li Peter Tipping Alex Bobik Ban-Hock Toh

BACKGROUND Heart attacks and strokes, leading causes of deaths globally, arise from thrombotic occlusion of ruptured vulnerable atherosclerotic plaques characterized by abundant apoptosis, large necrotic cores derived from inefficient apoptotic cell clearance, thin fibrous caps, and focal inflammation. The genesis of apoptosis and necrotic cores in these vulnerable atherosclerotic plaques remai...

Journal: :Molecules 2021

Curcumin, a natural polyphenolic compound present in Curcuma longa L. rhizomes, shows potent antioxidant, anti-inflammatory, anti-cancer, and anti-atherosclerotic properties. Atherosclerosis is comprehensive term for series of degenerative hyperplasic lesions such as thickening or sclerosis large- medium-sized arteries, causing decreased vascular-wall elasticity lumen diameter. Atherosclerotic ...

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