نتایج جستجو برای: atopy
تعداد نتایج: 8879 فیلتر نتایج به سال:
PURPOSE Atopy is an important cause of asthma. Few data on the prevalence of atopy or comparisons with clinical characteristics of asthma in Korean patients have been published. We evaluated the effects of atopy on clinical profiles and airway inflammation in Korean asthmatics. METHODS We retrospectively enrolled 1,492 asthmatics from the Cohort for Reality and Evolution of Adult Asthma in Ko...
BACKGROUND In high-income countries, allergy-related diseases (ARDs) follow a typical sequence, the 'Atopic March'. Little is known about the life-course of ARDs in the markedly different, low-income, tropical environment. We describe ARDs in a tropical, African birth cohort. METHODS Ugandan children were followed from birth to 9 years. ISAAC questionnaires were completed at intervals; doctor...
BACKGROUND Volatile organic compounds (VOCs) in concentrations found in both the work and home environments may influence lung function. We investigated the prevalence of airway responsiveness in workers exposed to VOCs. METHODS We used allergic skin tests, nonspecific airway hyperresponsiveness testing and questionnaires to study twenty exposed workers and twenty-seven control subjects. Atop...
IgE, and atopy. Results: We measured the total serum IgE of 155 children. The number of obese and normal weight children with family history of atopic disease who had high level of total serum IgE were 30 and 25 respectively, whereas these children who had normal level of total serum IgE were 6 and 15 respectively [OR 1⁄4 1.9 (95% CI 0.9-3.9)]. On the other hand, obese and normal weight childre...
Linkage of high-affinity IgE receptor gene with bronchial hyperreactivity, even in absence of atopy.
Asthma is a manifestation of bronchial hyperreactivity (BHR) and forms part of the spectrum of atopic disease. Some pedigree studies of atopy have suggested linkage with the high-affinity IgE receptor (Fc epsilon RI beta) gene on chromosome 11q13, but others find no linkage. The molecular genetics of asthma and BHR have not been studied in the general population. We examined the genetic linkage...
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