The short-term in vitro growth of Plasmodium falciparum parasites in the asexual erythrocytic stage and the in vitro activities of eight standard antimalarial drugs were assessed and compared by using RPMI 1640 medium supplemented with 10% nonimmune human serum, 10% autologous or homologous acute-phase serum, or 0.5% Albumax I (lipid-enriched bovine serum albumin). In general, parasite growth w...

INTRODUCTION The basophil activation test showing CD63 up regulation could be a specific and sensitive in vitro complementary text to the in vivo autologous serum skin test for the activity assessment of the patients suffering autoimmune chronic spontaneous urticaria. The aim of this study is to define the basophil activation test as a useful tool in clinical practice in order to identify those...

BACKGROUND The Human Immunodeficiency Virus (HIV) and the Tuberculosis (TB) co infection are contributory to each other in causing a progressive decline in the cell mediated immunity and a damage to the hepatobiliary system. The aim of our study was to estimate the extent of liver damage which was caused by these infections before the start of the therapy with hepatotoxic drugs like Antiretrovi...

BACKGROUND Zoledronic acid (ZOL) is widely used for treatment of glucocorticoid-induced osteoporosis. The most common adverse effects of ZOL treatment are post-dose symptoms. ZOL-induced hepatotoxicity has very rarely been reported. CASE REPORT Here, we described a 50-year-old Chinese woman who had vertebral fractures and severe back pain after glucocorticoid therapy for Behcet disease for 13...

BACKGROUND AND PURPOSE The evaluation of adenosine deaminase (ADA) activity in sera of patients with hepatitis should be considered a useful tool in the monitoring of their clinical status. In this study, we aimed to determine the relationship between viral load, transaminase levels, and serum ADA levels in hepatitis B virus (HBV)- and hepatitis C virus (HCV)-infected patients. METHODS Sevent...

Lymphocyte blastogenic studies to autologous leukemia cells were carried out in 35 patients with adult acute leukemia. The effects of serum on this response and correlation with studies of general immunocompetence were studied. Twenty-five of 35 patients had positive blastogenesis. Nine patients with acute myelogenous leukemia had complete or partial abrogation of this response in autologous se...

Lymphocyte blastogenic studies to autologous leukemia cells were carried out in 35 patients with adult acute leukemia. The effects of serum on this response and correlation with studies of general immunocompetence were studied. Twenty-five of 35 patients had positive blastogenesis. Nine patients with acute myelogenous leukemia had complete or partial abrogation of this response in autologous se...

Objective: Immune plasma therapy, a method employed for passive immunization, has been utilized as treatment modality based on historical precedents during the Covid-19 pandemic, global crisis resulting in unfortunate demise of countless individuals. The objective this study is to investigate impact immune therapy laboratory parameters and overall survival rate patients with pneumonia. Material...

introduction: one of the main mechanisms by which diabetic complications occur is an alteration of the structure and function of proteins due to hyperglycemia. aspirin (asa) affects cellular pathways through different mechanisms, including glycation inhibition and antioxidant activity. the aim of the present study, as a follow up to our previous one, is to investigate the effect of long-term, h...