نتایج جستجو برای: avoidance memory retention

تعداد نتایج: 357133  

Journal: :Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2005
R Walz R Roesler A Reinke M R Martins J Quevedo I Izquierdo

We studied the effects of infusion of nerve growth factor (NGF) into the hippocampus and entorhinal cortex of male Wistar rats (250-300 g, N = 11-13 per group) on inhibitory avoidance retention. In order to evaluate the modulation of entorhinal and hippocampal NGF in short- and long-term memory, animals were implanted with cannulae in the CA1 area of the dorsal hippocampus or entorhinal cortex ...

ابوطالبی چالشتری, مریم, رشیدی‌پور, علی, وفایی, عباسعلی,

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Banafshe Esmailzade, Iraj Sohrabi, Maliheh Nobakht, Nahid Rahbar Rooshandel, Pejman Mortazavi, Seyed Mohammad Hoseini, Shila Omidzahir,

Background: Alzheimer’s disease (AD) is a neurodegenerative disorder with progressive loss of cognitive abilities and memory loss. The aim of this study was to compare neuropathological changes in hippocampus and brain cortex in a rat model of AD. Methods: Adult male Albino Wistar rats (weighing 250-300 g) were used for behavioral and histopathological studies. The rats were randomly assigned t...

Journal: :Behavioral neuroscience 2000
A M Schneider N S Koven K A Lombardo D A Levin P E Simson

The effect of beta-adrenergic receptor blockade on retention in a mildly aversive passive-avoidance procedure was investigated. Rats were given passive-avoidance training--1 trial per day for 4 days-and were administered saline, the centrally and peripherally acting beta-adrenergic blocker propranolol (4 or 10 mg/kg ip), or the peripherally acting beta-adrenergic blocker sotalol (4 or 10 mg/kg ...

Journal: :Neurobiology of learning and memory 2016
Yaser Norozpour Mohammad Nasehi Vahid Sabouri-Khanghah Mohammad Torabi-Nami Mohammad-Reza Zarrindast

The α2 adrenergic receptors which abundantly express in the CA1 region of the hippocampus play an important role in the regulation of sleep and memory retention processes. Based on the available evidence, the aim of our study was to investigate consequences of the activation and deactivation of CA1 α2 adrenergic receptors (by clonidine and yohimbine, respectively) on the impairment of memory re...

2013
Nasrin Hosseini Hojjatallah Alaei Parham Reisi Maryam Radahmadi

BACKGROUND Alzheimer's disease was known as a progressive neurodegenerative disorder in the elderly and is characterized by dementia and severe neuronal loss in the some regions of brain such as nucleus basalis magnocellularis. It plays an important role in the brain functions such as learning and memory. Loss of cholinergic neurons of nucleus basalis magnocellularis by ibotenic acid can common...

Abasali Vafaei, Ali Rashidipour, John Bouresh, Mohammad Reza Sharifi,

There is strong evidence that two cerebral hemispheres are differentially involved in emotional memory and that amygdala is a key subcortical structure for emotional experience. The present research investigated the possible involvement of lateralization of basolateral amygdala (BLA) and central amygdala (CEA) in place avoidance memory. For this purpose, male Long-Evans rats (280-320 g) were im...

2015
Zeynab Sarlak Shahrbanoo Oryan Mehrnoush Moghaddasi

OBJECTIVES The cholinergic system plays an important role in learning and memory. This study investigated the effects of curcumin (turmeric extract) and the cholinergic system and their interaction on memory retention of passive avoidance learning in adult male Wistar rats. MATERIALS AND METHODS At first, an injection cannula was implanted in right ventricles of the animals. One week after th...

Journal: :Neuropharmacology 2004
R H Silva V C Abílio A L Takatsu S R Kameda C Grassl A B Chehin W A Medrano M B Calzavara S Registro M L Andersen R B Machado R C Carvalho R de A Ribeiro S Tufik R Frussa-Filho

Numerous animal and clinical studies have described memory deficits following sleep deprivation. There is also evidence that the absence of sleep increases brain oxidative stress. The present study investigates the role of hippocampal oxidative stress in memory deficits induced by sleep deprivation in mice. Mice were sleep deprived for 72 h by the multiple platform method-groups of 4-6 animals ...

Journal: :Neurosciences 2007
Mohandas K Rao Muddanna S Rao Gurumadhva S Rao

OBJECTIVE To investigate the role of Centella asiatica (CeA) fresh leaf extract treatment on the behavior, especially learning and memory, of adult rats. METHODS Adult rats (2.5 months old) were fed with 2, 4, and 6 ml/kg body of fresh leaf extract of CeA for 2, 4, and 6 weeks. After the treatment period the rats were subjected to spatial learning (T-Maze) and passive avoidance tests along wi...

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