Bacterial meningitis is a major cause of death and disability in children worldwide. Two human restricted respiratory pathogens, Streptococcus pneumoniae Haemophilus influenzae , are the causative agents bacterial meningitis, attributing to 200,000 deaths annually. These pathogens often part nasopharyngeal microflora healthy carriers. However, what factors elicit them disseminate invasive disea...

mucosal surfaces of the body provide a universal entry portal for all known and emerging infectious pathogenic microbes. therefore, it seems that special vaccination strategies are needed for vaccines that can hinder the entry capability of pathogenic microbes through the mucosal surfaces. lactic acid bacteria are widely used in the food industry and are presently applied as delivery vehicles i...

Culture of bronchoalveolar lavage fluid (BALF) is the gold standard for detection of pathogens in the lower airways in cystic fibrosis (CF). However, current culture results do not explain all clinical observations in CF, including negative culture results during pulmonary exacerbation and inflammation in the absence of pathogens. We hypothesize that organisms not routinely identified by cultur...

Bacterial pathogens are ubiquitous in soil and water - concurrently so are free-living helminths that feed on bacteria. These helminths fall into two categories; the non-parasitic and the parasitic. The former have been the focus of previous work, finding that bacterial pathogens inside helminths are conferred survival advantages over and above bacteria alone in the environment, and that accide...

Background: Infection is one of the most serious complications and leading cause of morbidity and mortality in patients with hematological-oncological disorders. We aimed to assess distribution of pathogens and their antibiotic resistance pattern in patients admitted to hematology-oncology department of Namazi Hospital, Shiraz from April 2016 to March 2017.  Methods: The current cross-sectiona...

Due to the emergence of bacterial resistance in phytopathogenic microorganisms, it is necessary search for new treatment alternatives these pathogens. Natural extracts are a potential source bioactive compounds that can act against such strains. The antibacterial activity Larrea tridentata bacteria with public health importance has been documented; however, few reports cover pathogens associate...