Adult male Sprague-Dawley rats weighing 175 to 250 grams were injected intravenously with 0.5-0.8 ml. of a four-hour culture of Escherichia coli (containing 4-7 x 108 organisms/ml.) in beef heart infusion broth. This particular strain was originally isolated from the urine of a patient with pyelonephritis and has been fully described elsewhere.' It is known that this organism is trapped by the ...

Initial Evaluation of Animals with Kidney Disease with a Focus on Chronic Diseases (CKD) For all animals with CKD, a thorough history and physical examination should be accompanied by complete clinical pathology testing, which includes a biochemical panel, hematology, and urinalysis with specific proteinuria tests and aerobic bacterial culture. Survey radiography ± abdominal ultrasonography and...

Pregnancy in end stage renal disease women who are on Hemodialysis has been considered a challenging event for both mother and fetus. Generally, outcomes of pregnancy in patients with end-stage renal disease (ESRD) have been considered to be extremely poor, and pregnancy in this group of patients is rather scarce. The frequency of conception is ranged from 0.3% per year in Belgium to 1.4% per y...

Objective(s):MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression. They have important roles in kidney development, homeostasis and disease, and participate in the onset and progression of tubulointerstitial sclerosis and end-stage glomerular lesions that occur in various forms of chronic kidney disease (CKD). In the present study, we elucidated the role of microR...

BACKGROUND The long-term health consequences of acute bacterial gastroenteritis remain uncertain. We studied the risk of hypertension and reduced kidney function after an outbreak of acute gastroenteritis due to contamination of a regional drinking water supply with Escherichia coli O157:H7 and Campylobacter species. METHODS A total of 1958 adults with no known history of hypertension or kidn...

Received April 2007 Accepted August 2007 INTRODUCTION Emphysematous pyelonephritis is an uncommon and severe acute bacterial infection of the kidney. Diagnosis is usually made very late due to changing manifestations and infrequent occurrence. On the other hand, xanthogranulomatous pyelonephritis is a rare severe renal infection which typically results in diffused destruction of the kidney in a...