SummaryBackground Operating rooms (ORs) have strict requirements regarding cleanliness. While existing standards concerning the ventilation and staff guidelines are theoretically sufficient to subvert threats posed by micro-organisms within room, there exist potential sources of contamination due human activity around area. Studies exploring this influence on distribution micr...

The aim of this prospective observational study was to determine those factors influencing bacterial colonization in patients with stable chronic obstructive pulmonary disease (COPD). Eighty-eight outpatients with stable COPD and 20 patients with normal spirometry and chest radiography (controls) had a fibreoptic bronchoscopy performed with topical aerosol anaesthesia. Bacterial colonization wa...

The oral cavity is a complex ecosystem in which several hundred microbial species normally cohabit harmoniously. However, under certain special conditions, the growth of some micro-organisms with a pathogenic potential is promoted, leading to infections such as dental caries, periodontal disease, and stomatitis. The physiology and pathogenic properties of micro-organisms are influenced by modif...

The emergence of nosocomial diseases driven by multidrug resistant bacteria is a major issue for our healthcare system. Mechanisms underlying multidrug resistance in these bacteria can be linked to the decreased permeability of bacterial membranes towards antibiotics, either by structural modifications inducing reduced passive diffusion, or by decreasing active uptake systems. Micro-organisms n...

The resolution of Chlamydophila abortus (Chlamydia psittaci serotype 1) infection is dependent on gamma interferon and CD8(+) T cells, and classically, B cells have been considered to play a minimal role in host defense. The role of B cells in the immune response was studied by using a model of infection in mice with genetically modified immunoglobulin M transmembrane domains ( micro MT). In th...

This study evaluated the induction of hairy roots in Perovskia abrotanoides Karel, a medicinally important member of Lamiaceae family, using different strains of Agrobacterium rhizogenes and various carbon supplies, for the first time. This research established an efficient Agrobacterium mediated transformation system for this plant species through bacterial strains including ATCC15834, TR105 a...

because of its kinetic nature and computational advantages, the lattice boltzmann method (lbm) has been well accepted as a useful tool to simulate micro-scale flows. the slip boundary model plays a crucial role in the accuracy of solutions for micro-channel flow simulations. the most used slip boundary condition is the maxwell slip model. the results of maxwell slip model are affected by the ac...

Bacterial biofilms can generate micro-heterogeneity in terms of surface structures. However, little is known about the associated changes in the physics of cell-cell interaction and its impact on the architecture of biofilms. In this study, we used the type IV pilus of Neisseria gonorrhoeae to test whether variation of surface structures induces cell-sorting. We show that the rupture forces bet...

OBJECTIVES A prospective surveillance study was conducted to investigate the epidemiology and patterns of antibiotic resistance among uropathogens from hospitalised children in Beira, Mozambique. Additionally, information regarding determinants of a urinary tract infection (UTI) was obtained. METHODS Bacterial species identification, antimicrobial susceptibility testing and extended-spectrum ...