background: advancement in the treatment of various types of cancer has led to greater patient survival. these treatments essentially have toxic effects on different kinds of cells, such as germ cells. infertility as one of the side effects of cancer treatment has changed the quality of life of young cancer survivors dramatically. melatonin is an antioxidant with receptors in the reproductive s...

conclusions tachyzoite of toxoplasma and dna of this parasite were observed in sub mucosa and muscles of the uterus and in the villis of placenta, but not in histological sections of the fetus. therefore, histological and molecular results were consistent. background toxoplasma gondii is an important zoonotic pathogen. vertical transmission of the parasite occurs when females were infected prim...

introduction: there are general concerns about the hazardous impacts of the cell phones radiation on the human health. in this study, the structural and biochemical changes of the mice kidney were assessed after cell phone exposure in. materials and methods: a total of 40 balb/c mice were randomly divided into the control and experimental groups. the experimental group exposed to cell phone dev...

cyclophosphamide (cp) is one of the anti-neoplastic drugs. despite its numerous clinical applications, it has devastating effects on the testicles and declines the sperm quality in treated patients. this study was aimed to investigate the protective effect of crocin in improving the toxicity induced by cp in reproductive system. in this study, 24 male adult mice (6 to 8 weeks) were randomly div...

background: due to common use of methylphenidate (mph) for the treatment of attention deficit hyperactivity disorder (adhd) and the role of the reproductive system in the production of gametes, studying the effects of this medication on the morphometry of testes, serum testosterone concentration, leydig cells function, and fertility rate was the aim of this study. methods: twenty seven male mic...

diethylstilbestrol (des) was widely used in the past, as the morning after contraception, but its application became extremely limited due to several complications including delayed clear cell adenocarcinoma in female infants. however, the use of des increased during the past decade for hormone replacement therapy. the aim of this study was to investigate possible teratogenicity of this synthet...

citrullus colocynthis (cct) is used in traditional medicine to inhibit the implantation of embryos. the objective of this study was to determine the number of embryos per pregnancy and the mortality rate in pregnant mice. 115 vaginal plug-positive mice were divided into 4 groups. the animals were given 30, 60 and 120 mg/kg hydroalcoholic extract of cct until 17th day of gestation. control group...

side effects of ciprofloxacin (cpfx), a widely used broad spectrum antibiotic with fluoroquinolone core, have been reported in different organs. in the present study we sought to elucidate the impact of ciprofloxacin on sperm chromatin integrity and sperm dna damage using aniline blue and acridine orange technique, respectively. the fertility potential in male mice was also evaluated. nmri male...

parasitic infections of rodents can compromise scientific research as well as the health of the animals and humans. based on previous studies, infection rate of parasitic helminths is different in various regions of iran. the current survey was aimed to determine endoparasitic helminths infection in 138 trapped rodents of kermanshah county, iran. mice and rats were trapped using metal snares fr...

reports indicate that one of the causes of harmful to the genital system, especially the testes stress. stress could be created secondarily after some pathological conditions such as neurological diseases or environmental factors. one of the causes of stress could be scary voices, such as cat voice for mice. in this study we aimed to investigate the testes parameters in the animals that were ex...