Customer order acceptance is an important process in make-to-order industries. Acceptance policies should operate such that a pre-specified delivery reliability is achieved, while maximizing resource utilization. By selecting orders with specific characteristics that maximize resource utilization, an important and often unforeseen effect occurs: the mix of orders changes such that the expected ...

In this paper, we consider the scheduling problem in which the jobs are first processed on a single machine and then delivered in batches by a single vehicle with limited capacity to the respective customers located at the vertices of a star-shaped network. The goal is to minimize the makespan. We present a 3/2-approximation algorithm for the identical job size case and a 2-approximation algori...

BACKGROUND AND THE PURPOSE OF THE STUDY Pectin derivatives have been utilized for colonic drug delivery (CDD). In this study the effects of different formulation variables upon the characteristics of pectinate microparticles (MPs) prepared by ionotropic gelation technique for colonic delivery of mesalazine was investigated. METHODS In-vitro drug release of MPs was studied using USP XXIV disso...

introduction: note taking while attending a ppt requires high activity of memory and writing process which ultimately leads to what is called “death by power point” referring to boredom and fatigue. to overcome this we planned to evaluate the impact of utilisation of uncompleted handouts given prior to ppt presentations. methods: final year mbbs students were divided in 2 batches, batch a and b...

Purpose: Inflammatory bowel disease (IBD) is a chronic, relapsing and often life-long disorder. The best way to tackle IBD is to develop a site targeted drug delivery. Methylprednisolone is a potent anti-inflammatory steroid. The relative potency of methylprednisolone to hydrocortisone is at least four is to one. The aim of the present research was to develop a colon targeted drug delivery for ...

This paper presents a comparison between batch and three different sets of fed batch fermentations forrhamnolipid production by Pseudomonas aeruginosa. The batch run was performed with 500 ml of culturemedium having the initial glycerol and sodium nitrate concentrations of 30 and 8.3 g/l, respectively. For a fedbatch run with nitrogen source in feed, 250 ml of the nitrogen exc...

Motivated by applications in porcelain-making companies, we consider a type of optimization problems for batch-processing operations. In production, single machine with fixed capacity is used to process jobs. Several jobs can be processed together if their total size no more than the capacity. Batch-position-based learning effects are considered because workers become skillful gradually after t...

Batch processes are commonly characterized by uneven trajectories due to the existence of batch-to-batch variations. The batch end-product quality is usually measured at the end of these uneven trajectories. It is necessary to align the time differences for both the measured trajectories and the batch end-product quality in order to implement statistical process monitoring and control schemes. ...

An integrated batch-to-batch control and within batch re-optimisation control strategy for batch processes using neural network models is presented in this paper. In order to overcome the difficulties in developing detailed mechanistic models, neural network models are developed from process operation data. Due to model-plant mismatches and unknown disturbances, the optimal control policy calcu...