نتایج جستجو برای: bbb p

تعداد نتایج: 1273346  

Journal: :Neuro-oncology 2022

Abstract Brain tumor associated edema is a significant cause of patient morbidity and mortality often requiring continual treatment with differing levels success across patients. Edema broad term that can indicate increased local water as well diffusely infiltrating cells. visualized hyperintense regions on T2-weighted (T2W) magnetic resonance imaging (MRI) typically blood-brain barrier (BBB) b...

Journal: :Microvascular research 2010
Wei Yuan Guanglei Li Min Zeng Bingmei M Fu

Previous studies have shown that the glycoprotein orosomucoid modulates permeability of peripheral microvessels to charged molecules by contributing to the net charge on the microvessel wall. To investigate whether or not orosomucoid also modulates the permeability of the blood-brain barrier (BBB) by a similar mechanism, we measured the permeability (P) of rat pial microvessels to similar-sized...

Journal: :Journal of lipid research 2015
Kelly Fellows Tomas Uher Richard W Browne Bianca Weinstock-Guttman Dana Horakova Helena Posova Manuela Vaneckova Zdenek Seidl Jan Krasensky Michaela Tyblova Eva Havrdova Robert Zivadinov Murali Ramanathan

The purpose of this work was to investigate the associations of serum cholesterol and apolipoproteins with measures of blood-brain barrier (BBB) permeability and CNS inflammation following the first clinical demyelinating event. This study included 154 patients [67% female; age, 29.5 ± 8.2 years (mean ± SD)] enrolled in a multi-center study of interferon β1-a treatment following the first demye...

Journal: :Publications of the Research Institute for Mathematical Sciences 2007

Journal: :iranian journal of basic medical sciences 0
mohammadamin hosseini kahnouei physiology-pharmacology research center, rafsanjan university of medical sciences, rafsanjan, iran hosseinali rezazadeh physiology-pharmacology research center, rafsanjan university of medical sciences, rafsanjan, iran ali roohbakhsh pharmaceutical research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran mohammad hossein mahmoodi physiology-pharmacology research center, rafsanjan university of medical sciences, rafsanjan, iran amir moghadam-ahmadi department of neurology, rafsanjan university of medical sciences, rafsanjan, iran mohammadreza zarisfi physiology-pharmacology research center, rafsanjan university of medical sciences, rafsanjan, iran

objective(s):hypothermia and decompressive craniectomy (dc) have been shown to be neuroprotective. this study was designed to evaluate neuroprotective effects of delayed singular or combination of dc and local hypothermia on stroke. materials and methods: cerebral ischemia was induced in 48 wistar rats assigned to 4 groups: control, decompressive craniectomy (dc), local hypothermia (lh), combin...

2017
Shahram Mashhadizadeh Yaghoub Farbood Mahin Dianat Ali Khodadadi Alireza Sarkaki

OBJECTIVES Cognitive defects such as learning and memory impairment are amongst the most repetitious sequelae after sever and moderate traumatic brain injury (TBI). It was suggested that ellagic acid (EA), an innate phenol product, display neuroprotective properties against oxidative and inflammatory damages after brain injury. The object of the current study was therapeutic properties of EA on...

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