In vivo studies were conducted to compare the activity of three non-steroidal anti-inflammatory drugs as inhibitors of urinary bladder carcinogenesis induced in B6D2F1 (BDF) mice by N-butyl-N-(4-hydroxybutyl)nitrosamine (OH-BBN). Mice received continuous dietary exposure to non-toxic doses of aspirin, sulindac or ketoprofen beginning 1 week prior to the first of eight weekly doses of 7.5 mg OH-...

Previously, high-order semi-implicit Picard integral deferred correction (SIPIDC) methods have been proposed for the time-integration of partial differential equations with two or more disparate time scales. The SIPIDC methods studied to date compute a high-order approximation by first computing a provisional solution with a first-order semi-implicit method and then using a similar semi-implici...

In this paper, the pressure correction finite element method is proposed for 2D/3D time-dependent thermomicropolar fluid equations. The first-order and second-order backward difference formulas (BDF) are adopted to approximate time derivative term, stability analysis error estimation of semi-discrete scheme proved. Finally, some numerical examples given show effectiveness reliability method, wh...

D03PFF integrates a system of linear or nonlinear convection-diffusion equations in one space dimension, with optional source terms. The system must be posed in conservative form. Convection terms are discretized using a sophisticated upwind scheme involving a user-supplied numerical flux function based on the solution of a Riemann problem at each mesh point. The method of lines is employed to ...

In this article we discuss a combination between fourth-order finite difference methods and fourth-order splitting methods for 2D parabolic problems with mixed derivatives. The finite difference methods are based on higher-order spatial discretization methods, whereas the timediscretization methods are higher-order discretizations using CrankNicolson or BDF methods. The splitting methods are hi...

A novel bit-detect-and-forward (BDF) relaying scheme based on repetition coding with the relay is proposed, significantly improving the robustness to impairments proper to free-space optical (FSO) communications such as unsuitable alignment between transmitter and receiver as well as fluctuations in the irradiance of the transmitted optical beam due to the atmospheric turbulence. Closed-form as...