Gonadal steroid hormones act throughout the body to elicit changes in gene expression that result in profound effects on reproductive physiology and behavior. Steroid hormones exert many of these effects by binding to their respective intracellular receptors, which are members of a nuclear receptor superfamily of transcriptional activators. A variety of in vitro studies indicate that nuclear re...

Ketamine is a drug that is commonly used for anesthesia and analgesia worldwide. Although it has an excellent safety profile, cognitive and psychotomimetic adverse effects are commonly associated with its administration. This review describes the clinical applications, potential adverse events, neurobiological, and behavioral effects of ketamine used at subanesthetic doses in humans.

Trust is an essential component of transactions that occur over time. The amount of trust accorded to others is typically conditioned on multiple factors, including knowledge of the other party, the history of interactions, and the context of exchange. Determining who to trust and who to distrust is especially important in modern societies with largely impersonal exchange (Vernon L. Smith, 2003...

OF DISSERTATION

The glucocorticoid hormones corticosterone (CORT) and cortisol influence numerous physiological, morphological, and behavioral functions. However, few studies have addressed possible relationships between individual differences in glucocorticoid concentrations and whole-animal performance or metabolism. Because CORT is important in glucose regulation and energy metabolism and can influence acti...