Multiple sclerosis (MS), a demyelinating disease of the central nervous system, is more commonly seen in women. It has been associated with both anterior and intermediate uveitis as well as retinal vasculitis. Ocular inflammation may develop concurrent with, prior to, or after the development of neurologic signs and symptoms. Patients with MS have an approximately 1% chance of developing intrao...

OBJECTIVE Uveitis has been increasingly recognised as a side effect of rifabutin regimens in the prophylaxis and treatment of Mycobacterium avium intracellulare (MAI) infection. This study describes the clinical features and analyses the factors associated with rifabutin induced uveitis. DESIGN Retrospective observational study. SETTING Tertiary care institution, The Royal Hospitals NHS Tru...

Ocular signs are common in systemic sarcoidosis. Upwards of 50 per cent. of affected patients develop a granulomatous anterior uveitis, and fundus lesions are frequently observed. Ocular findings due to central nervous system involvement are less frequent, but can be the initial complaint. The subject of central nervous system involvement in sarcoidosis has been reviewed by Colover (I948) and W...

A 74-year-old woman developed bilateral uveitis with high Epstein-Barr virus (EBV) DNA load in the vitreous fluid without lymphoma cells. Four years after the onset, T2-weighted contrast-enhanced MRI revealed hyperintense lesions in the right occipital and parietal lobe. A biopsy resulted in the diagnosis of extranodal NK/T-cell lymphoma nasal type (ENKL). The repeat region of LMP1, an EBV gene...

INTRODUCTION Syphilis is a sexually transmitted, systemic, chronic infection that can affect all structures of the eye from cornea to optic nerve.1,2 The British Ocular Syphilis Study (BOSS) reported an annual incidence of intraocular syphilis of 0.3 per million UK adult population based on 2014 data. Bilateral ocular involvement was present in 56%, and the mean presenting Snellen visual acuity...

We report a rare case of chronic refractory uveitis in a patient with childhood-onset cyclic neutropenia (CN). A 19-year-old woman, who had a history of CN beginning at age 2, presented with bilateral chronic nongranulomatous uveitis, complicated cataract, retinal vasculitis, cystoids macular edema, and vitreous hemorrhage. She had recurrent episodes of oral ulcers, tonsillitis, genital ulcers,...

Objectives To determine the prevalence of vitreomacular interface (VMI) disorders in patients with Behçet's uveitis and assess the relationship between VMI disorders and clinical characteristics. Materials and Methods The macular optical coherence tomography (OCT) images of 160 eyes of 96 patients with Behçet's uveitis who were being followed in the Uvea-Behçet's clinic were assessed retrospe...

ABSTRACT This report aims to describe the effectiveness of a unilateral intravitreal dexamethasone implant (Ozurdex®) used for treatment cystoid macular edema in patient with recurrent intermediate uveitis. Bearing mind adverse effects prolonged use systemic corticosteroids, objective here was provide less damaging form intervention, and also demonstrate safety patients who fail respond convent...

A case history of a 15-year-old schoolgirl with fluctuating bilateral uveitis, bilateral stromal keratitis with vascularisation, and bilateral deafness associated with tinnitus and balance disturbance is described. Three years from the onset of her clinical signs she died of a sudden cardiac arrest caused by endocarditis associated with valvular and arterial lesions. Chlamydia psittaci was isol...