AIM To evaluate the clinical value of various imageological methods in diagnosing the pancreato-biliary diseases and to seek the optimal procedure. METHODS Eighty-two cases of pancreato-biliary diseases confirmed by surgery and pathology were analyzed. There were 38 cases of cholelithiasis, 34 cases of pancreato-biliary tumors and 10 other cases. The imageological methods included B-US, CT, E...

There are many reports on the appearance of a typical isoenzyme of alkaline phosphatase (EC 3.1.3.1; API)2 in serum of patients suffering from biliary obstruction. According to the characteristics observed in various studies, this API has variouslybeen termed “high molecular weight” (1), “origin,” “stationary,” “particulate” (2), “bile,” “cholestatic,” “pathological biliary” (3, 4), and “koinoz...

Shepherd HA, Royle G, Ross APR, Diba A, Arthur M and Colin-Jones D (1988) Endoscopic biliary endoprosthesis in the palliation ofmalignant obstruction of the distal common bile duct." a randomized trial. British Journal ofSurgery; 75.’1166-1168 A total of 52 jaundiced elderly patients who had malignant obstruction of the distal common bile duct and who required palliative biliary decompression w...

Gall stone ileus is a mechanical bowel obstruction caused by passage of gall stones from the biliary system through a biliaryenteric fistula with impaction within lumen of the bowel. It is an uncommon complication of biliary stone disease, accounting for only 2% of all cases of intestinal obstruction. Gall stone ileus is, however, more common in the elderly and accounts for approximately 25% of...

Biliary atresia is characterized by the progressive obliteration of extra- and intrahepatic biliary duct system leading to the obstruction of bile flow in infancy. The cause(s) of biliary atresia remain unclear and many surgical options for bypassing the atretic segment have been described.1-3 Biliary atresia may be associated with small bowel atresia.  The surgical interventions for biliary dr...

The biliary duct is an extremely rare site for colon cancer metastasis. It often leads to a diagnostic dilemma, since primary cholangiocarcinoma (potentially treatable with surgery) has a similar presentation. This paper highlights our experience with 5 consecutive patients who had colon malignancy with biliary metastasis, and prognosis of their disease. Five patients, with a history of primary...

The etiology and pathogenesis of bile duct obstruction in children with biliary atresia are largely unknown. We have previously reported that, despite phenotypic heterogeneity, genomic signatures of livers from patients display a proinflammatory phenotype. Here, we address the hypothesis that production of IFN-gamma is a key pathogenic mechanism of disease using a mouse model of rotavirus-induc...

Pancreatic cancer is devastating due to its poor prognosis. Patients require a multidisciplinary approach to guide available options, mostly palliative because of advanced disease at presentation. Palliation including relief of biliary obstruction, gastric outlet obstruction, and cancer-related pain has become the focus in patients whose cancer is determined to be unresectable. Endoscopic stent...