Although remarkable advances have been reported in high-throughput sequencing, the ability to aptly analyze a substantial amount of rapidly generated biological (DNA/RNA/protein) sequencing data remains critical hurdle. To tackle this issue, application natural language processing (NLP) sequence analysis has received increased attention. In method, sequences are regarded as sentences while sing...

Polymer brushes are macromolecular structures with polymer chains tethered to a surface resembling brush. They have shown variety of uses in biological applications. Because the nature crafted polymers, functionalized surfaces exhibit unique functions such as low friction, altered adhesion, protein binding and selective adsorption. Functionalization can be controlled by changing parameters graf...

Adoptive T cell transfer, involving the ex vivo expansion of T lymphocytes, is a viable therapeutic approach for both infectious diseases and cancer, with demonstrated efficacy in treating melanoma, Epstein-Barr virus, and HIV-related infections. However, T cell transfer by clonal expansion is not clinically feasible as it does not consistently generate therapeutic quantities of T cells. Effort...

Adoptive T cell transfer, involving the ex vivo expansion of T lymphocytes, is a viable therapeutic approach for both infectious diseases and cancer, with demonstrated efficacy in treating melanoma, Epstein-Barr virus, and HIV-related infections. However, T cell transfer by clonal expansion is not clinically feasible as it does not consistently generate therapeutic quantities of T cells. Effort...

Fluorescence is one of the most important analytical methods used in biological studies. In the past decade or two, instrumentation in this field has greatly advanced, and now it is possible to detect single photons or fluorescent molecules [1,2], or break the Abbe diffraction limit to distinguish two points spaced less than 50 nm apart [3]. Concurrently, the development of improved fluorescent...