نتایج جستجو برای: biomarker screening

تعداد نتایج: 282581  

2016
Rebecca Myerson Lisandro Colantonio Monika Safford David Meltzer

This paper investigates the consequences of removing barriers to information by studying screenings that enable medical treatment of asymptomatic health conditions. We consider two unintended consequences of reducing out-of-pocket costs of screening, as is done in the Affordable Care Act. First, lower-cost screenings attract patients with lower demand for information, who may also have lower de...

2013
Li Ying Qi Wang

The development of early and personalized diagnostic protocols is considered the most promising avenue to decrease mortality from cancer and improve outcome. The emerging microfluidic-based analyzing platforms hold high promises to fulfill high-throughput and high-precision screening with reduced equipment cost and low analysis time, as compared to traditional bulky counterparts in bench-top la...

ژورنال: یافته 2018

Background: Lung cancer is one of the most common cancers around the world, and a major cause of death. The KRAS and NRAS genes could cause malfunction in signal transduction and cell cycle regulation. Materials and Methods: In this study, the expression level of KRAS and NRAS biomarkers among 50 lung cancer patients in comparison with 50 normal individuals was investigated. Total RNA from blo...

2016
Tara J Wu Karen Smith-McCune Miriam Reuschenbach Magnus von Knebel Doeberitz May Maloba Megan J Huchko

OBJECTIVE A biomarker with increased specificity for cervical dysplasia compared with human papillomavirus (HPV) testing would be an attractive option for cervical cancer screening among HIV-infected women in resource-limited settings. p16(INK4a) has been explored as a biomarker for screening in general populations. DESIGN A 2-year cross-sectional study. SETTING 2 large HIV primary care cli...

Journal: :Cancer prevention research 2014
Janet L Brandsma Malini Harigopal Nancy B Kiviat Ying Sun Yanhong Deng Daniel Zelterman Paul M Lizardi Veronika S Shabanova Angelique Levi Tian Yaping Xinyuan Hu Qinghua Feng

An accurate biomarker for the follow-up of women positive for human papillomavirus type 16 (HPV16) DNA may improve the efficiency of cervical cancer prevention. Previously, we analyzed all 113 HPV16 CpGs in cervical cytology samples and discovered differential methylation at different stages of premalignancy. In the current study, we identified a methylation biomarker consisting of a panel of 1...

2015
Kim Y. C. Fung Bruce Tabor Michael J. Buckley Ilka K. Priebe Leanne Purins Celine Pompeia Gemma V. Brierley Trevor Lockett Peter Gibbs Jeanne Tie Paul McMurrick James Moore Andrew Ruszkiewicz Edouard Nice Timothy E. Adams Antony Burgess Leah J. Cosgrove

BACKGROUND The majority of colorectal cancer (CRC) cases are preventable by early detection and removal of precancerous polyps. Even though CRC is the second most common internal cancer in Australia, only 30 per cent of the population considered to have risk factors participate in stool-based test screening programs. Evidence indicates a robust, blood-based, diagnostic assay would increase scre...

Journal: :International journal of cancer 2010
Kenneth Wayne Marshall Steve Mohr Faysal El Khettabi Nadejda Nossova Samuel Chao Weisheng Bao Jun Ma Xiao-Jun Li Choong-Chin Liew

Colorectal cancer (CRC) is often curable and preventable using current screening modalities. Unfortunately, screening compliance remains low, partly due to patient dissatisfaction with faecal/endoscopic testing. Recent guidelines advise CRC screening should begin with risk stratification. A blood-based test providing clinically actionable CRC risk information would likely improve screening comp...

Journal: :emergency journal 0
somayeh valadkhani mohammad jalili associate professor, tehran university of medical sciences, tehran, iran elham hesari hadi mirfazaelian

introduction: acute coronary syndrome accounts for more than 15% of the chest pains. recently, hess et al. developed north american chest pain rule (nacpr) to identify very low-risk patients who can be safely discharged from emergency department (ed). the present study aimed to validate this rule in eds of two academic hospitals. methods: a prospective diagnostic accuracy study was conducted on...

ژورنال: Hormozgan Medical Journal 2013
Aghayousefi, A.R. , Alipoor, A. , Shaghaghi, F. , Sharif, N. ,

Introduction: Coping ways with stress in coronary heart disease can lead to significant changes in levels of IL-6 Immunologic Biomarker. The aim of this study was to examine the relationship between coping ways with stress and IL-6 immunologic biomarker in coronary heart disease patients. Methods: In this experimental study, the subjects were 44 patients with confirmed CHD, admitted to the priv...

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