Biomaterial implants and devices increase the risk of microbial infections due to the biofilm mode of growth of infecting bacteria on implant materials, in which bacteria are protected against antibiotic treatment and the local immune system. Matrix-metalloproteinases (MMPs) and cell surface integrin receptors facilitate transmigration of inflammatory cells toward infected or inflamed tissue. T...

Biofilm Repellent Commensals In article number 2101410, Muhammad Imran Rahim and co-workers report a novel coating of commensal microflora on biomaterial surfaces that can prevent the colonization infectious biofilm-forming oral pathogens. This remains biocompatible with human cells, suggesting an advanced therapeutic approach to control difficult-to-treat biomaterial-related infections in cavi...

spinal cord injury (sci) results in the damage of motor and sensory pathways. the molecular and cellular structure of the injury milieu has been shown to be vital for endogenous regeneration in most tissues. regeneration of injured central nervous system (cns) is limited by damaged cell environment. biomaterial scaffolds can reconstruct injured cns tissue following sci by promoting the migratio...

introduction: natural biomaterials and growth factors are key factors in tissue engineering. the objective of the present study was to evaluate transforming growth factor beta 1 (tgf-β1) and curcumin on proliferation and differentiation of nasal-derived chondrocyte seeded on the fibrin glue scaffold. methods: chondrocytes were isolated from nasal samples. nasal-derived chondrocytes were seeded ...

introduction: mineral trioxide aggregate (mta) has been suggested for root-end filling, vital pulp therapy, apical plug, perforations repair, and root canal filling. since the introduction of mta in 1993, many studies about this material have been published. the aim of this survey was to illustrate statistical information about published articles in pubmed-index journals vis-à-vis the various a...

in recent years the science of tissue engineering has emerged as a powerful tool for the development of a novel set of tissue replacement parts and technologies. recent advances in the fields of biomaterials, stem cell technologies, growth factor field and biomimetics have created a unique set of opportunities for investigators to fabricate lab-grown tissues from combination of extracellular ma...

the fabrication of complex-shaped parts out of (wt %) co-28cr-6mo alloy by three-dimensional printing (3dp) was studied using two grades of the alloy with average particle sizes of 20 and 75 μm. to produce sound specimens, 3dp processing parameters were tuned. the sintering behavior of the powders was characterized by the dilatometric analysis. batch sintering in argon atmosphere at 1280 °c for...

In food and chemical industry, supercritical fluid extraction is an environmental-friendly separation technique, which plays an important role in biomaterial processing. In this paper, a dynamic optimisation model for supercritical fluid extraction is proposed by combining a transformation based genetic algorithm and the Peng-Robinson equation of state. The proposed dynamic model for the relati...

The permeability characteristics of biomaterials are critical parameters for a variety of implants. To analyse the permeability of membranes made from crosslinked ultrathin gelatin membranes and the transmigration of cells across the membranes, we combined three technical approaches: (1) a two-chamber-based permeability assay, (2) cell culturing with cytochemical analysis and (3) biochemical en...