This data article shows how the recombinant Chinese Hamster Ovary (CHO) cells are located in the interstices of the matrix fibers of a CellTank bioreactor after completion of a perfusion culture, supporting the article entitled "Very high cell density perfusion of CHO cells anchored in a non-woven matrix-based bioreactor" by Zhang et al. [1]. It provides a visualization of the cell distribution...

Citation: Jakobs G, Labrenz M, Rehder G, Hietanen S, Kießlich K, Vogts A, Blumenberg M and Schmale O (2016) A Bioreactor Approach to Investigate the Linkage between Methane Oxidation and Nitrate/Nitrite Reduction in the Pelagic Oxic-Anoxic Transition Zone of the Central Baltic Sea. Front. Mar. Sci. 3:145. doi: 10.3389/fmars.2016.00145 A Bioreactor Approach to Investigate the Linkage between Met...

We study the stochastic model for bioremediation in a bioreactor with ideal mixing. The dynamics of the examined system is described by stochastic differential equations. We consider an optimal control problem with quadratic costs functional for the linearized model of a well-stirred bioreactor. The optimal control is based on the optimal robust state estimates. The approximate optimal solution...

Enzyme surface concentration and permeate stream obtained in the membrane module with a dynamically formed biocatalyst layer were determined experimentally using two different, polymeric membranes. Correlations were formulated to calculate these values. It was found that their variability range was so big that when controlling the transmembrane pressure and turbulence of a retentate stream, the...

The present work deals with the kinetics of rifamycins production and degradation by Amycolatopsis mediterranei in submerged culture using industrial medium. Cultivations were conducted in shake flasks and stirred tank bioreactor to evaluate the influence of transfer of process to higher scale on overall process kinetics and to obtain better understanding for the kinetics of rifamycins producti...

An economical bioreactor designed for evaluating the biogas potential of particulate biomass is described. The bioreactor uses a simple stirring apparatus, called the Bordeaux stirrer, to enable gas-tight mixing of fermentation cultures. The apparatus consists of a low-rpm motor connected to a bent steel stir rod, which is placed in a length of flexible plastic tubing inserted through a rubber ...

Biofiltration for volatile organic compound control in waste gas streams is best operated at steady contaminant loadings. To provide long-term stable operation of a biofilter under adverse contaminant feeding conditions, an integrated bioreactor system with a gas separation membrane module installed after a biofilter was proposed for styrene treatment. Styrene was treated effectively, with aver...

Strategies are needed to improve repopulation of decellularized lung scaffolds with stromal and functional epithelial cells. We demonstrate that decellularized mouse lungs recellularized in a dynamic low fluid shear suspension bioreactor, termed the rotating wall vessel (RWV), contained more cells with decreased apoptosis, increased proliferation and enhanced levels of total RNA compared to sta...

The mathematical model of the integrated process of mercury contaminated wastewater bioremediation in a fixed-bed industrial bioreactor is presented. An activated carbon packing in the bioreactor plays the role of an adsorbent for ionic mercury and at the same time of a carrier material for immobilization of mercury-reducing bacteria. The model includes three basic stages of the bioremediation ...

Streptomyces griseus was cultured in three different bioreactors in a medium containing chitin flakes. When a conventional bioreactor stirred by two sets of Rushton impellers and operated at high speed was used, the yield of streptomycin (3.1 mg/l) was the highest observed and occurred at approximately 500 hours. Cultivation of S. griseus in a bioreactor stirred at low speed by a U-shaped paddl...