abstract background: streptococcus mutans in the oral cavities sable to produce mutacin (bacteriocin-like substances) with antibiotic properties. the aim of this study was to investigate the frequency and expression of genes encoding mutacins typei, ii, iii and iv and also two of 8 genes in a cluster encoding the putative bacteriocins, the designated bsm 283, bsm 299, bsm 423, bsm 1889c, bsm 18...

INTRODUCTION .......................................................................................................................................................547 GENERAL ASPECTS OF b-LACTAM COMPOUNDS........................................................................................548 BIOSYNTHESIS OF PENICILLINS AND CEPHALOSPORINS: AN OUTLINE.............................................

Transcription factors of the basic Helix-Loop-Helix (bHLH) family play a central role in cell proliferation, determination, and differentiation. In plants, the regulatory functions of bHLHs in phenylpropanoid biosynthesis have been well established with regard to other interacting-proteins; i.e., MYB and WD40 repeat proteins. On the other hand, those in alkaloid biosynthesis are greatly limited...

BACKGROUND Streptomyces albus J1074 produces glycosylated antibiotics paulomycin A, B and E that derive from chorismate and contain an isothiocyanate residue in form of paulic acid. Paulomycins biosynthesis pathway involves two glycosyltransferases, three acyltransferases, enzymes required for paulic acid biosynthesis (in particular an aminotransferase and a sulfotransferase), and enzymes invol...

Long non-coding RNAs (lncRNAs) are widely available transcription products of more than 200 nucleotides with unrecognizable coding potential. A large number lncRNAs have been identified in different plants. involved various basic biological processes at the transcriptional, post-transcriptional and epigenetic levels as key regulatory molecules, including regulation flowering time reproductive o...

Anthocyanins are flavonoid compounds that protect plant tissues from many environmental stresses including high light irradiance, freezing temperatures, and pathogen infection. Regulation of anthocyanin biosynthesis is intimately associated with environmental changes to enhance plant survival under stressful environmental conditions. Various factors, such as UV, visible light, cold, osmotic str...

Abstract Larval metamorphosis, the planktonic larvae transited into benthic juveniles, is a short important phase for mollusks. However, information about mechanism of its larval settlement and metamorphosis Pinctada fucata martensii still limited. In this study, metabolomic transcriptomic approaches were applied to assess metabolic transcript changes among different stage groups P. f. understa...

Drought is a major limiting factor of Brassica napus (rapeseed) and potassium (K) plays important roles in rapeseed drought tolerance. Previous studies have reported that cultivars characterized by different K status showed contrasting However, the molecular mechanism underlying tolerance remains unclear. In this study, comparative transcriptome analysis was conducted between drought-tolerant c...

Abstract Salvia miltiorrhiza is a model medicinal plant with significant economic and value. Its roots produce group of diterpenoid lipophilic bioactive components, termed tanshinones. Biosynthesis regulation tanshinones has attracted widespread interest. However, the methylome S. not been analysed regulatory mechanism DNA methylation in tanshinone production largely unknown. Here we report sin...