نتایج جستجو برای: birc5

تعداد نتایج: 294  

2016
Piruz Motamedinia Anna N. Scott Kendall L. Bate Neda Sadeghi Guillermo Salazar Edan Shapiro Jennifer Ahn Michael Lipsky James Lin Greg W. Hruby Ketan K. Badani Daniel P. Petrylak Mitchell C. Benson Michael J. Donovan Wayne D. Comper James M. McKiernan Leileata M. Russo

PURPOSE The analysis of exosome/microvesicle (extracellular vesicles (EVs)) and the RNA packaged within them (exoRNA) has the potential to provide a non-invasive platform to detect and monitor disease related gene expression potentially in lieu of more invasive procedures such as biopsy. However, few studies have tested the diagnostic potential of EV analysis in humans. EXPERIMENTAL DESIGN Th...

Journal: :PLoS ONE 2007
Byungwoo Ryu Dave S. Kim Amena M. DeLuca Rhoda M. Alani

BACKGROUND Gene expression profiling has revolutionized our ability to molecularly classify primary human tumors and significantly enhanced the development of novel tumor markers and therapies; however, progress in the diagnosis and treatment of melanoma over the past 3 decades has been limited, and there is currently no approved therapy that significantly extends lifespan in patients with adva...

2011
Iver Nordentoft Lars Dyrskjøt Julie S Bødker Simone Bertz Torben F Ørntoft Karin Birkenkamp-Demtroder

Thank you for reviewing our manuscript entitled " Increased expression of Transcription Factor TFAP2α correlates with chemosensitivity in advanced bladder cancer " and for giving us the opportunity to submit a revised version. We have now included a 'Competing interests' section and correctly placed the Author's contributions and Acknowledgement section. We have found the comments from the revi...

Journal: :PLoS Biology 2006
Liza Gross

Background. Gene expression profiling has revolutionized our ability to molecularly classify primary human tumors and significantly enhanced the development of novel tumor markers and therapies; however, progress in the diagnosis and treatment of melanoma over the past 3 decades has been limited, and there is currently no approved therapy that significantly extends lifespan in patients with adv...

Journal: :Molecular biology of the cell 2009
Petra Obexer Judith Hagenbuchner Thomas Unterkircher Nora Sachsenmaier Christoph Seifarth Günther Böck Verena Porto Kathrin Geiger Michael Ausserlechner

The phosphatidylinositol 3-kinase (PI3K)-protein kinase B (PKB) pathway regulates survival and chemotherapy resistance of neuronal cells, and its deregulation in neuroblastoma (NB) tumors predicts an adverse clinical outcome. Here, we show that inhibition of PI3K-PKB signaling in human NB cells induces nuclear translocation of FOXO3/FKHRL1, represses the prosurvival protein BIRC5/Survivin, and ...

Journal: :International Journal of Ecophysiology 2023

Oral mucosal cancer is a type of that develops from the lining oral cavity (mucosa). The main risk factors are smoking and drinking alcohol. pathogenesis involves various interrelated etiologies such as alcohol consumption, human papilloma virus (HPV), patients who have undergone hemopoietic stem cell transplants (stem transplants). Meanwhile, it does not rule out possibility internal genetics....

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