of Blood-Flow-Volume Measurement To the Editor: With great interest we read in Stroke that a working group around Soustiel1 compared cerebral blood flow (CBF) as measured by xenon clearance technique with blood-flow-volume (BFV) measurements from the internal carotid artery (ICA). Soustiel et al found well-correlated data, ie, correlation coefficients 0.75, in a total of 77 measurements. As a c...

The measurement of cerebral blood flow by means of the nitrous oxide method of Kety and Schmidt (1) or the krypton-85 (Kr85) technique of Lassen and Munck (2) requires a steady state of at least ten minutes, for it is not until the end of such a period that the uptake of the gas by the brain can be estimated indirectly from its concentration in cerebral venous blood. These methods are, therefor...

Skin irritation is mostly a multifactorial process. Competitive effects of different chemical irritants are well known. This study investigates the influence of a thermal stimulus on skin pre-irritated with sodium lauryl sulfate (SLS). Seventy-seven volunteers were patch-tested with SLS 0.25% and 0.5% for 48 h. Water served as control. Skin reaction was evaluated by measurement of transepiderma...

• The Kety-Schmidt method for measurement of regional blood flow was first applied to the heart by Eckenhoff et al. These investigators employed coronary sinus catheterization to measure myocardial blood flow with nitrous oxide. The use of a radioactive gas and an external detector for the measurement of organ blood flow was investigated by Conn, Lewis et al., and Lassen et al. The radioactive ...

OBJECTIVE Volumetric flow measurement with Doppler ultrasound is useful in assessing blood flow as part of an evaluation of arteriovenous fistula maturity in patients undergoing hemodialysis. In this study, we assessed both accuracy and variability in volumetric flow measurements obtained using modern and commercially available ultrasound systems and an in vitro experimental setup. METHODS Vo...