Medical physiology laboratories, traditionally devoted to animal experimentation, face unprecedented difficulties linked to cost, staffing, instrumentation, and the use of animals. At the same time, laboratory experiences with living creatures play a unique role in medical education. In this article we describe the use of venipuncture and subsequent blood analysis, with medical students serving...

Our circulatory system is composed of numerous elements that are responsible for transport of blood and delivery of essential nutrients and gases to vital downstream tissues. Among these components that make up our circulation is vascular smooth muscle (VSM), the primary muscular and contractile element of blood vessels and regulator of many blood vessel functions. This is of particular importa...

Physiology has a long history of two-way interactions with clinical medicine. Physiology as an experimental discipline emerged in North America during the 1820s as Beaumont studied the gastric secretions of the French-Canadian trapper Alexis St. Marin who had a posttraumatic fistula that permitted easy access to the gastric contents (42, 48). What follows are a few thoughts on why physiology ma...

BACKGROUND Medical resources and resource allocation including operating room and blood utilization are of prime importance in the modern combat environment. We hypothesized that easily measurable admission physiologic criteria and injury site as well as injury severity calculated after diagnostic evaluation or surgical intervention, would be strongly correlated with resource utilization and in...

In this work, a lumped-parameter Windkessel model of the cardiovascular system that simulates biomechanical parameters human physiology is presented. The object-oriented platform provided by MATLAB-based modeling environment SIMSCAPE employed to compute blood pressures and flows in each heart chamber at various sites vascular tree. hydraulic domain allows determination hemodynamics intuitively ...

in the mouse: principles, progress, and prospects In vivo assessment of neurocardiovascular regulation You might find this additional info useful... intact animal to the cellular, subcellular, and molecular levels. It is published 12 times a year (monthly) by the American lymphatics, including experimental and theoretical studies of cardiovascular function at all levels of organization ranging ...