Glycated haemoglobin A1c (HbA1c) gives an integrated plasma glycaemia for the previous 2-3 months and its measurement is central in the management of diabetic patients. However in many developing countries because kits/regents or expertise for HbA1c measurement are not always available and the test must be conducted on fresh whole blood samples, HbA1c tests are not routinely performed Thus, thi...

OBJECTIVES Recently, concern has been expressed about the transfusion of older red blood cells after cardiac surgery. We tested the hypothesis that longer storage of transfused red blood cells increases the risk of early and late mortality in patients who undergo coronary artery bypass grafting. METHODS We retrospectively analyzed data of patients who underwent isolated coronary artery bypass...

background: excessive ordering of blood components imposes heavy costs to blood transfusion centers and increases the amount of blood product wastage due to lack of their use. in recent years, attempts have been made against unnecessary blood and blood product requests in our country. we aimed to investigate the frequency of blood and blood product wasting in healthcare centers of yazd city in ...

OBJECTIVE To examine the effect of the duration of storage of serum and whole blood at different controlled temperatures on the concentrations of both serum free-beta-human chorionic gonadotropin (beta-hCG) and pregnancy-associated plasma protein-A (PAPP-A) in first-trimester screening for aneuploidies. METHODS The concentrations of free beta-hCG and PAPP-A were measured in samples collected ...

; a quantity, which is effectively overcome by the fresh living blood. In 102 .bottles of blood collected consecutively for storage between 22nd November, 1939, and 22nd April, 1941, ; (date of starting storage and date of writing this note, respectively) not a single bottle was found contaminated on inspection (by sight and smell). Between the same dates no accidents, resulted from 75 consecut...

Despite improvements to standard treatments (atropine, oxime) and intensive care management, the mortality associated with organophosphate (OP) poisoning has not substantially decreased. In this study, we evaluated the role of packed red blood cells (RBCs) transfusion in acute OP poisoning. Patients diagnosed with OP poisoning were included in this prospective study, and then were transfused wi...

Blood transfusion is a fundamental therapy in numerous pathological conditions. Regrettably, many clinical reports describe adverse transfusion's drawbacks due to red blood cells alterations during storage. Thus, the possibility for a blood bank to ameliorate the quality of the erythrocyte concentrates units is crucial to improve clinical results and reduce transfusion adverse occurrences. Leuk...

BACKGROUND Before-storage WBC reduction by filtration appears to be an effective way to prevent transfusion-associated complications. It also has superiority over WBC reduction at the time of transfusion (bedside), due to the many variables associated with such practice and the difficulty in performing adequate quality control. To determine the adaptability of collection systems containing in-l...