Objective(s): Multifunctional nanomedicine is the new generation of medicine, which is remarkably promising and associated with the minimum toxicity of targeted therapy. Distribution and transport of nanoparticles (NPs) in the blood flow are essential to the evaluation of delivery efficacy. Materials and Methods: In the present study, we initially designed a phantom based on Murray’s mini...

In diabetic patients, vascular disease and autonomic dysfunction might compromise cerebral autoregulation and contribute to orthostatic intolerance. The aim of our study was to determine whether impaired cerebral autoregulation contributes to orthostatic intolerance during lower body negative pressure in diabetic patients. Thirteen patients with early-stage type 2 diabetes were studied. We cont...

Estimation of blood velocities using ultrasound and time-domain cross-correlation is investigated. The measurement principle is introduced and the basic properties of the cross-correlation function is discussed. Expressions for the variance of the estimates of the peak location are given showing the innuence of integration time, transducer bandwidth and signal-to-noise ratio. It is also shown t...

The correlation between the increase in velocity of blood flow in both the internal carotid and vertebral arteries during a carotid compression and the cerebrovascular resistance (CVR) was investigated in 11 patients with chronic ischemic cerebrovascular disease and 4 without organic brain lesions. The velocity of blood flow was measured by an ultrasonic Doppler flowmeter. CVR was calculated fr...

OBJECTIVE To give a detailed evaluation on main pulmonary artery blood velocity patterns, in patients with ischemic heart disease and to provide recommendations for pulsed Doppler sample volume placement, in order to optimize cardiac output estimation. METHODS Using magnetic resonance phase and esophageal color Doppler velocity mapping in 12 patients with ischemic heart disease and undergoing...

Sedimentation of red blood cell aggregates was experimentally investigated by optical imaging. Suspensions of red blood cell at low hematocrit were obtained from blood of healthy donors. The velocity of three-dimensional red blood cell aggregates was measured using particle image velocimetry. The magnitude and spatial correlation functions of the velocity fluctuations of the settling aggregates...