Introduction: In patients with low initial bone mass, alendronate treatment causes small increases in DXA derived areal bone mineral density (BMD) and large decreases in fracture incidence. An increase in bone balance (the difference between bone formed and that resorbed per remodeling cycle) is often cited as the primary cause of increased BMD in clinical trials. Although some evidence exists ...

OBJECTIVE Most of phenylketonuria (PKU) develops bone turnover impairment and low bone mineral density (BMD). Measurements of BMD reflect only bone mineral status but not the dynamics of bone turnover. Bone markers are a noninvasive tool useful for the assessment of bone formation and bone resorption processes. Our study was to assess the levels of bone markers in PKU in order to select a screen...

Bone mineral density (BMD) is the tool for diagnosing osteoporosis in older adults. However, BMD alone is not sufficient for deciding who should be given treatment at either the individual patient or the public health level. Robust, scientifically validated algorithms that combine BMD with other clinical risk factors provide more accurate assessment of fracture probability. New guidelines for m...

Daily subcutaneous administration of bovine parathyroid hormone (PTH)(1-34) stimulates bone formation and increases bone mass in rat tibiae, femora and lumbar spine. However, the effects of PTH on the whole body bone mineral content and density determined by dual energy x-ray absortiometry (DEXA) have not been previously reported in rats. Eighteen-month-old intact female rats were subcutaneousl...

background : the aim of this study was to demonstrate similarities and differences between mothers and daughters regarding dietary and non-dietary risk factors for bone fractures and osteoporosis. methods : the study was carried out in 2007-2010 on 712 mothers (29-59 years) and daughters (12-21 years) family pairs. in the sub-sample (170 family pairs) bone mineral density (bmd) was measured for...

OBJECTIVES Osteoporosis induces the reduction of bone mass and screening for low bone mineral density (BMD) by dual-energy x-ray absorptiometry (DXA) has been the current gold standard test to determine osteoporosis. Panoramic radiography is widely used in dentistry for routine examination of jaws. The objective of this study was to determine the relationship between the mandibular angle (MA) v...

BACKGROUND Several reports have suggested low bone mineral density (BMD) in patients with adolescent idiopathic scoliosis (AIS). We determined bone mineral status in patients with AIS to evaluate the effect of brace treatment on BMD. METHODS BMD was measured in 46 patients (mean age, 17.8 ± 4.9 years) with AIS (17 with brace and 29 without brace) by dual-energy X-ray absorptiometry scan and c...

background there is evidence in support of low bone density in young patients with disorders of phenylalanine metabolism; however, little is known about muscle and fat mass in these patients, especially in those with mild hyperphenylalaninemia (mhpa). objectives we aimed to evaluate body composition of children and adolescents with early-diagnosed disorders of phenylalanine metabolism. patients...

Graves' (GD) hyperthyroidism leads to reduced bone mineral density (BMD) accompanied by accelerated bone turnover. Ample studies have identified association between estrogen receptor (ESR1) gene polymorphism and decreased BMD and osteoporosis. In contrast, number of publications that link ESR1, BMD and Graves' disease is limited. The purpose of this study was to identify the association between...

OBJECTIVE Treatment for childhood leukaemia induces many risk factors for development of decreased bone mineral density (BMD). Physical activity is also known to affect BMD. The aim was to study BMD and markers of bone turnover in a well-defined group of survivors of acute lymphoblastic leukaemia (ALL) who had all reached final height as well as peak bone mass, taking both previous treatment an...