BACKGROUND It remains unknown whether continuous or scheduled intermittent bolus local anesthetic administration is preferable for adductor canal perineural catheters. Therefore, we tested the hypothesis that scheduled bolus administration is superior or noninferior to a continuous infusion on cutaneous knee sensation in volunteers. METHODS Bilateral adductor canal catheters were inserted in ...

y mathematically extending the former model for the theoretical description of the aerosol bolus dispersion the behavior of particle pulses in diseased lung structures was simulated. The geometry used for healthy lungs was modified in two aspects: First, a modeling of possible airway obstructions, which usually occur in patients with chronic bronchitis, chronic asthma or cystic fibrosis, was ca...

In this manuscript, we describe the potential role of the pericardial space as a drug delivery reservoir to administer angiogenic agents to the heart resulting in functionally significant angiogenesis with single bolus basic fibroblast growth factor (bFGF) delivery. We also describe a percutaneous subxyphoid pericardial access technique that is safe, rapid, and reliable.

Spherical monodisperse ferromagnetic iron oxide particles of 1.9 μm geometric and 4.2 μm aerodynamic diameter were inhaled by 13 healthy non-smokers using the shallow bolus technique. The bolus width was 100 ml and the penetration front depth was 150+/-27 ml. The mean flow rate during inhalation and exhalation was 250 ml/s. The Fowler dead space and the phase1 dead space of the airways was 282+...

The effects of brief and sustained pharmacologic alpha-adrenergic stimulation on the coronary arterial circulation were compared in awake pigs. Phenylephrine was administered into the left anterior descending coronary artery (LAD) either as a bolus (eight pigs) or as a 15-minute infusion (eight pigs), with myocardial blood flow measured by the radioactive microsphere technique. Flow in the dist...

Introduction: The objective of this study was to describe the modalities responses observed following realization a bolus methylprednisolone in children treated for nephrotic syndrome pediatric nephrology unit Abidjan order assess need its our practice. Methods: we carried out descriptive and analytical cross-sectional patients followed up having benefited from administration 3 boluses at dosag...

OBJECTIVE The aim of this study was to find the most appropriate technique for postmastectomy chest wall (CW) and lymphatic irradiation. MATERIALS AND METHODS Partially wide tangent, 30/70 photon/electron mix, 20/80 photon/electron mix and CW and internal mammary en face electron field, were studied on computerized tomography (CT) scans of 10 left breast carcinoma patients and dosimetric calc...

Introduction: The present study aimed to generate intensity-modulated beams with Aluminium compensating filters for a conventional telecobalt machine based on the outputs of a treatment planning system (TPS) performing forward planning and cannot simulate directly the compensating filter. Materials and Methods: In order to achieve the beam intensity modulation during treatment planning with th...