BACKGROUND Patients with disabling pain and loss of shoulder function with associated proximal humeral bone loss following shoulder arthroplasty have limited reliable treatment options. Our objective was to report the results, obtained as part of a prospective outcomes study, of the use of a reverse shoulder prosthesis-allograft composite in these patients. METHODS Between 2002 and 2005, 353 ...

Background: Giant cell tumor (GCT) of bone is a relatively common type benign involving the epiphyseal region tubular bones, but GCT rarely occurs at hand (1–4% all GCT). within tends to be more aggressive and recurs rapidly in than other locations. Most authors prefer curettage or resection with reconstruction maintain anatomical functional integrity.Case Report: A 27-year-old man chief compla...

BACKGROUND The medial collateral ligament (MCL) is the main static stabilizer of the medial knee. The surgical treatment was recommended in cases with serious medial collateral ligament insufficiency combined with multi-ligament injuries and chronic symptomatic medial instability. Several surgical techniques have been described for the MCL reconstruction, while potential problems including dono...

Increased stability has been reported with both autografts and allografts for anterior cruciate ligament (ACL) reconstruction. However, meta-analysis has shown significantly lower overall knee stability rates and more than double the abnormal stability rate with allografts. Some issues surrounding allograft sterilization (ie, risk of disease transmission) are unresolved, and cost is also a conc...

Introduction RTI Biologics, Inc. (RTI) currently produces allograft demineralized bone matrix (DBM) paste products that are manufactured under strict aseptic conditions using single donors. All donors are subjected to rigorous screening, prior to processing, to ensure that no transmissible pathogens are present in donor material. In addition, a terminal sterilization procedure has been introduc...

Extramedullary hematopoiesis (EMH), defined as the presence of hematopoietic elements outside of the medullary cavity of bone, has been reported in patients with various hematopoietic neoplasms including myelofibrosis. EMH commonly occurs in the liver and spleen (resulting in hepatosplenomegaly) and uncommonly involves the kidney. EMH involving the allograft kidney has not been reported in Engl...

OBJECTIVE The high risk of nonunion represents a challenge in vertebral surgery, thus stimulating new strategies to improve fusion rates. We investigated the effect of 2 different bone grafts and amniotic fluid application on radiologically and histologically evaluated vertebral fusion in an experimental rat model. MATERIALS AND METHODS Forty-eight 24-week-old Sprague Dawley rats were include...

In order to investigate the osteoinductive properties of allograft used in impaction grafting and the effect of strain during impaction on these properties, we designed an in vitro experiment to measure strain-related release of bone morphogenetic protein-7 (BMP-7) from fresh-frozen femoral head allograft. A total of 40 10 mm cubes of cancellous bone were cut from ten samples of fresh-frozen fe...

PurposeTo determine whether surgeon volume affects revision rate following primary anterior cruciate ligament reconstruction (ACLR) with allograft and to impacts tissue type used.MethodsAll patients aged 14 years or older who underwent ACLR at a large hospital system between January 2015 December 2019 minimum 2-year follow-up were included. Patients double-bundle ACLR, multiligament reconstruct...

The most common techniques for the replacement of post-resection bone defects in patients with tumors are modular and individualendoprosthetics bioreconstructive interventions. following issues require solution: improvement development techniquesfor fixation segmental allograft recipient bone, study remodeling processes conditions andcytostatics (chemotherapy drugs) action, quality. Objective. ...