BACKGROUND Fat mass is variably associated with bone mass, possibly due to differential mechanical and biological effects of fat mass. We examined the association of fat mass with bone mass in a lean population. OBJECTIVE To investigate association between hip bone mineral density and fat and lean mass in a cross-sectional study from southern India. DESIGN The Andhra Pradesh Children and Pa...

BACKGROUND Our randomized, placebo-controlled supplementation study of 160 rural Gambian children aged 8.3-11.9 y showed that an increase in calcium intake of 714 mg/d for 12 mo resulted in a 5% increase in forearm bone mineral acquisition and a 22% decrease in plasma osteocalcin concentration, a bone formation marker, but had no effect on height or bone dimensions. OBJECTIVE We investigated ...

Objective. In patients scheduled to undergo total joint arthroplasty of the hip, the bone quality around the joint affects the safety of prosthetic implantation. Bone strength is clinically assessed by measuring bone mineral density (BMD); therefore we asked if BMD is important to orthopaedic surgeons performing hip arthroplasty. Methods. In a 14-question survey, we asked about treatment patter...

Growth hormone (GH) has profound effects on linear bone growth, bone metabolism and bone mass. The GH receptor is found on the cell surface of osteoblasts and osteoclasts, but not on mature osteocytes. In vitro, GH stimulates proliferation, differentiation and extracellular matrix production in osteoblast-like cell lines. GH also stimulates recruitment and bone resorption activity in osteoclast...

Chronic hemoglobinopathies like thalassemia are associated with many osteopathies like osteoporosis. Methods. This observational study was carried out to compare the bone mineral density (BMD) in transfusion dependent thalassemics with that of healthy controls. Thirty-two thalassemia patients, aged 2-18 years, and 32 age and sex matched controls were studied. The bone mineral concentration (BMC...

OBJECTIVES To study bone mineral density (BMD) and standard serum biochemical indices among newly diagnosed and already diagnosed cases of Celiac Disease (CD) on gluten free diet for at least one year. METHODS This hospital based analytic, observational study was done at a tertiary care centre, from April 2013 through June 2014. Thirty six children (20 females) with untreated CD at diagnosis ...

BACKGROUND Children with chronic intestinal failure (IF) treated with long-term parenteral nutrition (PN) may present with low bone mineral density (BMD). The cause may reflect small body size or suboptimal bone mineralization. OBJECTIVE We assessed growth and bone health in children with severe IF. DESIGN Height, weight, and fracture history were recorded. The lumbar spine bone mass was me...

Using a cluster sampling method, a group of menopausal women from three geographic areas in Tehran were asked to participate in the study. Demographic data was obtained using a questionnaire. Subjects were than referred to perform bone mass densitometry (BMD). The relationship between various variables (i.e. age of menarche, number of years of endogenous estrogen exposure, ... ) with minera...

Areal bone mineral density (BMD) is the most widely used densitometric parameter. However, this approach makes it difficult to understand the structural basis of bone diseases, because a large number of bone properties are integrated into a single number. This is exemplified in the present case of a 27-year-old woman with osteogenesis imperfecta type I. Peripheral quantitative computed tomograp...

Dual energy X-ray absorptiometry (DXA) was used to make total body and regional measurements of bone mineral content, bone mineral density, and bone area during the growth of pigs from 3 to 138 kg. In all, 1,053 total body scans were performed on 587 live pigs. Regional measurements consisted of the front legs, trunk, and back legs. In addition, bone mineral density readings were recorded for t...