We consider the problem faced by a retail chain that must select what mutual-substitute items to display in each one of its stores maximize revenues. The number cannot exceed limit space capacity store. Customers purchase product maximizes their utility, which depends on price, travel cost store, and reservation known retailer. retailer can set different price markdowns at products. considers d...

BACKGROUND The relationship between congenital hypothyroidism (CH) and multiple pregnancy has not been fully studied in Japan. METHODS Complete nationwide data of assisted reproductive technology (ART) in Japan from 2005 to 2009 presented by the Japan Society of Obstetrics and Gynecology, which include information on CH and birth defects were used for analyses. Diseases were reclassified acco...