Objective(s): Exposing to stress may be associated with increased production of reactive oxygen species (ROS). Therefore, high level of oxidative stress may eventually give rise to accumulation of oxidative damage and development of numerous neurodegenerative diseases. It has been presented that brain-derived neurotrophic factor (BDNF) supports neurons against various neurodegenerative conditio...

Brain-derived neurotrophic factor (BDNF) is a neurotrophin that regulates neuronal survival and growth during development. Effects of BDNF on neuronal transmission in the hippocampus, cortex, cerebellum and basal forebrain are important for learning and memory processes [1]. Reduced BDNF may affect synaptic efficiency and connectivity in schizophrenia that is hypothesized to underpin signs and ...