INTRODUCTION Breast density, a strong breast cancer risk factor, is usually measured on the projected breast area from film screen mammograms. This is far from ideal, as breast thickness and technical characteristics are not taken into account. We investigated whether volumetric density measurements on full-field digital mammography (FFDM) are more strongly related to breast cancer risk factors...

Introduction:There is considerable amount of controversy about the long term effects of multiparity and duration of breast-feeding on maternal bone mineral density after menopause. This study was conducted to determine whether multiple pregnancy and prolonged duration of breast-feeding are independent predictors of low bone mass in post-menopausal Kurdish women. M...

BACKGROUND The appearance of the female breast viewed by mammography varies considerably from one individual to another because of underlying differences in the relative proportions of fat, connective tissue, and glandular epithelium that combine to create a characteristic pattern of breast density. An association between mammographic patterns and family history of breast cancer has previously ...

Previous twin and family studies indicate that the familial aggregation of breast density is due (in part) to genetic factors. Whether these genetic influences are shared with other breast cancer risk factors, however, is not known. Using standard film-screen mammography, we screened 550 women, including 611 pairs of sisters, from the Old Order Amish population of Lancaster County, Pennsylvania...

This project is to develop an automated breast density segmentation system. Breast density has been shown to be a key indicator of breast cancer risk. Currently the primary computational system for analyzing breast density is a semiautomated segmentation system that requires a radiologist to set thresholds for the segmentation algorithm. This results in reader variability, which reduces the val...

Breast density is a well-known breast cancer risk factor. Most current methods of measuring breast density are area based and subjective. Standard mammogram form (SMF) is a computer program using a volumetric approach to estimate the percent density in the breast. The aim of this study is to evaluate the current implementation of SMF as a predictor of breast cancer risk by comparing it with oth...