Aims Exposure of the heart to radiation increases risk ischaemic disease, proportionate mean dose (MHD). Radiotherapy techniques including proton beam therapy (PBT) can reduce MHD. The aims this study were quantify MHD reduction achievable by PBT compared with volumetric modulated arc in breath hold (VMAT-BH) patients pectus excavatum (PEx), identify an anatomical metric from a computed tomogra...

Introduction: Radiotherapy (RT) plays a major role in the management of breast cancer. Cardiac Toxicity is an important late complication of radiotherapy for left sided Breast cancer. Cardiac morbidity can be minimized through careful treatment planning. Aim: To study the variation of dose to the heart by change in the depth of normalization point during Radiotherapy planning. Settings and desi...

BACKGROUND Ethnic and socioeconomic inequities in use of breast cancer adjuvant therapy are well documented in many countries including the USA, and are known to contribute to lower breast cancer survival among minority ethnic and socioeconomically deprived women. We investigated ethnic and socioeconomic inequities in use of adjuvant radiotherapy and chemotherapy in a cohort of women with invas...

PURPOSE Results of the American College of Surgeons Oncology Group (ACOSOG) Z0011 trial indicated that complete axillary node dissection (ALND) may not be warranted in some breast cancer patients with low tumor burden who are undergoing breast-conserving surgery following whole-breast irradiation. However, this study did not address patients undergoing mastectomy or those undergoing breast-cons...

PURPOSE Surgical clips are used as a target for postoperative breast radiotherapy, and displacement of surgical clips would result in inaccurate delivery of radiation. We investigated the displacement range of surgical clips in the breast during postoperative radiotherapy following breast-conserving surgery. METHODS A total of 178 patients who received breast-conserving surgery and postoperat...

BACKGROUND AND OBJECTIVE The role of adjuvant radiotherapy to the regional nodes in women with T1 to T2 breast cancer and one to three positive nodes is controversial. This study compared and analyzed the prognosis of patients with T1-T2 breast cancer with one to three positive nodes after modified radical mastectomy with or without postoperative radiotherapy. METHODS The cases of 434 women p...

background: delivering the maximum dose to tumor while achieving the minimum dose delivery to normal tissue; is the most important goal in external radiotherapy. diode in vivo dosimetry is widely considered to be an important tool for quality improvement of patient care in external radiotherapy. uncertainty in dose delivery should fall within 5% of the prescribed dose as recommended by internat...

background: this two-arm, randomized clinical study aimed to compare efficacy between topical alpha ointment and topical hydrocortisone cream (1%) in the healing of radiation-induced dermatitis in breast cancer patients. methods: the inclusion criteria comprised newly pathologically proven, locally advanced breast cancer (treated with modified radical mastectomy followed by sequential adjuvant ...

External radiotherapy following surgery for breast carcinoma may induce radiation injury to the lungs in a number of patients. Two types of injury are recognized that are temporally related to radiotherapy; an acute pneumonitis-like illness and fibrosis, with abnormalities confined to the radiation port (1). However, the spectrum of radiotherapy-induced sequelae may be more diverse. Two patient...