background:   although the majority of soft tissue masses are benign, it is important to consider malignancy in differential diagnoses. because most soft tissue sarcomas present as a painless mass, clinicians must watch for signs suggestive of malignancy, including large size, rapid growth, and site deep into the deep fascia.the purpose of this study was to determine the relative prevalence acc...

background pancreatic neuroendocrine tumors (pnets) are rare tumors with variable malignant potential, prognosis, and survival. we aimed to assess the characteristics of patients with non- functional pnet  in our hospital . methods from nov 2010 to nov 2013 , all patients who came to endosonography unit of shariati  hospital , tehran , iran , and   had pancreatic lesions were assessed . tumor s...

tumor size seems to be a determinant in the prognosis of early cervical cancer. patients with tumor size greater than 4 cm (bulky) in diameter have worse outcome.' the purpose of this study was to compare the efficacy of preoperative combined chemoradiation and neoadjuvant chemotherapy (narc) programs followed by radical hysterectomy in stage ib - lib bulky cervical cancer. from september ...

adult solid tumors: the highest risk of thromboembolism from the disease burden itself and related treatments, survival benefit of extensive cytoreductive surgery to minimize residual tumor even in cases of peritoneal seeding, and the strongest hereditary portion in adult solid tumors. Risk factors for venous thromboembolic disease includes active cancer, advanced stage, cancer type such as gyn...

Tumor size seems to be a determinant in the prognosis of early cervical cancer. Patients with tumor size greater than 4 cm (bulky) in diameter have worse outcome.' The purpose of this study was to compare the efficacy of preoperative combined chemoradiation and neoadjuvant chemotherapy (NArC) programs followed by radical hysterectomy in stage Ib - lIb bulky cervical cancer. From September ...

UV-induced DNA damage is repaired by nucleotide excision repair (NER) that corrects bulky helix-distorting lesions across the whole genome and essential for preventing mutagenesis skin cancer. Here we show METTL14 (methyltransferase-like 14), a critical component of m6A RNA methyltransferase complex, promotes through regulating mRNA methylation-mediated translation NER factor DDB2 suppresses tu...