The research of the first named author is supported in part by the KOSEF Grant R01-2005-000-10771-0 of The Republic of Korea. He also would like to thank the Centre de Mathematiques et Informatiques, Université de Provence, Aix-Marseille 1 (France) for its hospitality at the final stage of this work. Both authors thank the American Institute of Mathematics for its hospitality during a portion o...

OBJECTIVE This study defines the relationship between salivary beta-2 microglobulin (β2-M) and intensity of uremia in male patients diagnosed with chronic renal failure (CRF). MATERIALS AND METHODS In total of 42 males were enrolled in a case-control study. There were 21 cases of CRF and 21 control cases. We collected 10cc of saliva plus 5 cc of blood from all patients to determine β2-M, bloo...

Purpose: To explore the protective effect of glycyrrhizin in rats with nephrotic syndrome (NS) induced by adriamycin (ADR). Methods: 36 Sprague Dawley (SD) male rats were divided into control, untreated and glycyrrhizin treatment groups. The NS rat model was established by injecting ADR twice in the untreated and in the glycyrrhizin treatment groups. Rats in the glycyrrhizin treatment group wer...

BACKGROUND Kidney dysfunction is prevalent and impacts prognosis in patients with acute decompensated heart failure (ADHF). However, most previous reports were from a single hospital, limiting their generalizability. Also, contemporary data using new equation for estimated glomerular filtration rate (eGFR) are needed. METHODS AND RESULTS We analyzed data from the ARIC Community Surveillance f...

BACKGROUND Simple tools for risk stratification of patients with acute heart failure (AHF) are an unmet clinical need, particularly regarding long-term mortality. METHODS We prospectively enrolled 610 consecutive patients presenting to the emergency department with AHF. The diagnosis of AHF was adjudicated by two independent cardiologists. The classification and regression tree (CART) analysi...

objective(s): global cerebral ischemia-reperfusion (gcir) causes disturbances in brain functions as well as other organs such as kidney. our aim was to evaluate the protective effects of ellagic acid (ea) on certain renal disfunction after gcir. materials and methods: adult male wistar rats (n=32, 250-300 g) were used. gcir was induced by bilateral vertebral and common carotid arteries occlusio...

Objective This study aims to describe the overall cumulative effect of sevoflurane on kidney function in healthy patients in terms of mean plasma creatinine, blood urea nitrogen (BUN), creatinine clearance, urinary protein, and glucose excretion at 24 and 72 hours post-anesthesia. Data retrieval A systematic literature search using MEDLINE and EMBASE as primary search engines was conducted. A...

BACKGROUND Endothelin-1 (ET-1) is a vasoconstrictor peptide that mediates cell proliferation, fibrosis, and inflammation. ET-1 has 2 receptors A and B. OBJECTIVES The present study investigated whether administration of ET-1 receptor type A antagonist leads to protect cisplatin (CP) induced nephrotoxicity in ovariectomized-estradiol (Es) treated rats. MATERIALS AND METHODS Thirty-six ovarie...