quantitative serum level measurements of gc , cp , c3 , igg , iga and 1gm were carried out on 102 patients with esophageal carcinoma following laryngectomy, in comparison with 66 healthy individuals as controls, in gonbad area, north east of iran. the procedure of radioinimuno-diffusion by standard m partigen plates was used for the measurements. a significant decrease was observed in gc level ...

telomerase activation is one of the main pathways to immortalize cancer cells. in many kinds of cancer cells, this special reverse transcriptase stabilizes and elongates telomeres and prevents telomere erosion that naturally occurs in every cell division. esophageal cancer is the fifth most frequent cause of cancer death worldwide, and is highly associated with alcohol, smoking, cultural habits...

Background & Aims: Breast cancer is the second most common cancer in women, with the peak frequency of a decade lower than the global age. The aim of this cross sectional study is to estimate the burden of breast cancer in women in Western Azerbaijan Province in 2013. Materials & Methods:  In this cross-sectional study, the information needed to calculate YLD and YLL creating the total DA...

background : although, family history of cancer is an important risk factor for upper gastrointestinal cancers development, but limited information is available on the upper gastrointestinal cancers associated with family history in iran. the purpose of this study was to define upper gastrointestinal cancers risk associated with family history of cancer. methods : this study was conducted as a ...

Background & Aims: The burden of premature mortality is used to prioritize health problems. The purpose of this study was to estimate the burden of premature mortality due to colorectal cancer in Golestan from 2011 – 2015. Materials & Methods: In this sequential cross-sectional study, based on the province mortality registration data and standard expected years of life lost (SEYLL), the burden...

studies undertaken during the last 5 years in the babol research station of the institute of public health research, teheran university, with the collaboration of the international agency for research on cancer in the caspian littoral and ardabil area in the north of iran has indicated the presence of cancer in 48 different sites. the five more prevalent types of cancer found in that area in or...

Background: In the radiotherapy of patients with esophagus and breast cancer, the heart receives a significant dose of radiation that might cause heart complications. Thefore, the aim of the current study was to evaluate the effects of esophagus and left breast cancer radiotherapy on the cardiac function and to determine the relationship between the dosimetric parameters and ejection fraction (...

As a crucial event involved in the metastasis and relapse of esophageal cancer, c-Met overexpression has been considered as one of the culprits responsible for the failure in patients who received radiochemotherapy. Since c-Met has been confirmed to be pivotal for cell survival, proliferation and migration, little is known about its impact on the regulation of radiosensitivity in esophageal can...

most patients with gastrointestinal cancers refer to the health centers at advanced stages of the disease and conventional treatments are not significantly effective for these patients. therefore, using modern therapeutic approaches with lower toxicity bring higher chance for successful treatment and reduced adverse effects in such patients. the aim of this study is to evaluate the effect of av...