BACKGROUND Treatment of infectious diseases is becoming more challenging with each passing year. This is especially true for infections caused by Pseudomonas aeruginosa, an opportunistic pathogen with the ability to rapidly develop resistance to multiple classes of antibiotics. OBJECTIVES This study was conducted to determine the prevalence of metallo-β-lactamase (MBL)-producing strains among...

Objectives: Current study aimed to investigate how Pseudomonas aeruginosa and Escherichia coli isolates from clinical environmental sources respond antimicrobial agents.Methods: 40 samples were studied: (a) one burn (n=20), (b) different water soil (n=20). Identification of was done by analyzing colony morphology, microscopic examination, confirmed using the VITEK®2 Compact. All subjected susce...

BACKGROUND Topical antimicrobials are employed for prophylaxis and treatment of burn wound infections despite no established susceptibility breakpoints, which are becoming vital in an era of multidrug-resistant (MDR) bacteria. We compared two methods of determining topical antimicrobial susceptibilities. METHODS Isolates of Pseudomonas aeruginosa, methicillin-resistant Staphylococcus aureus (...

OBJECTIVE To identify Pseudomonas aeruginosa (P. aeruginosa) from the skin biopsy specimens in burn wound infections by multiplex polymerase chain reaction (M-PCR) and detection of antimicrobial susceptibility of isolates from culture. METHODS We conducted this cross-sectional study in 140 patients with wound infections who admitted to the referral burn center of Motahari, Tehran, Iran, durin...

The studies of the prevalence of Pseudomonas aeruginosa in burn wounds contamination in the ward were carried out. From a total of 166 Pseudomonas aeruginosa strains, 104 (62.7%) were obtained from freshly admitted burn wounds inmates where the isolates predominated in second-degree burns 45 (43.3%), followed by first-degree 38(36.5%) and thirddegree 21(20.2%). From long term patients, a total ...

Multi-drug resistant (MDR) strains of Acinetobacter baumannii are responsible for an increasing number of opportunistic infections in hospitals. This study determined the prevalence of MDR A. baumannii isolates from intensive care units in a large tertiary-care hospital in Ismailia, Egypt, and the occurrence of different beta-lactamases in these isolates. Biotyping and antimicrobial susceptibil...

Acinetobacter baumannii is a leading pathogen responsible for nosocomial infections. The emergence of carbapenem-resistant A. baumannii (CRAB) has left few effective antibiotics for clinicians to use. To investigate the temporal evolutionary relationships among CRAB strains, we collected 248 CRAB isolates from a Chinese burns institute over 3 years. The prevalence of the OXA-23 gene was detecte...

the objective of this study was to determine the phenotypic characteristics of kpc-producing pseudomonas aeruginosa and acinetobacter baumannii isolates. a case report study was performed at a tertiary burn care centre in tehran,  iran.  nine  isolates  of pseudomonas  aeruginosa  and  acinetobacter baumannii from a hospitalized case were isolated. the identity of isolates was confirmed and the...

Amikacin clearance can be increased in burn injury, which is often complicated by renal insufficiency. Little is known about the impact of renal replacement therapies, such as continuous venovenous hemofiltration (CVVH), on amikacin pharmacokinetics. We retrospectively examined the clinical pharmacokinetics, bacteriology, and clinical outcomes of 60 burn patients given 15 mg/kg of body weight o...

BACKGROUND Burns provide a suitable site for bacterial multiplication and are more persistent richer sources of infection than surgical wounds. Staphylococcus aureus is one of the most frequently isolated pathogens in both community and hospital practices. The objective of this study was to address the prevalence and antibiotic susceptibility patterns of S. aureus isolated from burn wound infec...