BACKGROUND Hypertrophic scar is one of the most common complications and often causes the disfigurement or deformity in burn or trauma patients. Therapeutic methods on hypertrophic scar treatment have limitations due to the poor understanding of mechanisms of hypertrophic scar formation. To throw light on the molecular mechanism of hypertrophic scar formation will definitely improve the outcome...

for the first time we have used eyelid skin expansion to facilitate reconstruction of selected patients with shortage of lid skin (e.g. for burn scar and after excision of tumors). this method allows for a controlled increase in skin, need for reconstruction, and offers many advantages over grafted skin transfered from a distance. color, texture, thinness, delicacy and adnexal structures are ae...

Standard approaches to evaluate scar formation within histological sections rely on qualitative evaluations and scoring, which limits our understanding of the remodelling process. We have recently developed an image analysis technique for the rapid quantification of fibre alignment at each pixel location. The goal of this study was to evaluate its application for quantitatively mapping scar for...

BACKGROUND Wound healing is widely discussed in the medical literature. This study compared the healing effect of aloe vera extract and silver sulfadiazine in burn injuries in experimental rat model. METHODS Sixteen rats were randomly assigned to one of two groups, each group 8 rats. A deep second-degree burn on the lower back and 3(rd) degree burn on upper back of each rat were created with ...

Modifi cations of traditional pressure gloves for improved performance in scar fl exion contracture prevention and fi ngertip circulation inspection Dear editor, Scar hyperplasia and contracture may occur both during the spontaneous healing process of burn injuries and after surgical correction of burn-injury-related hand dysfunction or deformity such as ulnar claw. Pressure gloves, capable of ...

Few biopharmaceutical preparations developed from biologicals are available for tissue regeneration and scar management. When developing biological treatments with cellular therapy, selection of cell types and establishment of consistent cell banks are crucial steps in whole-cell bioprocessing. Various cell types have been used in treatment of wounds to reduce scar to date including autolog and...

BACKGROUND The patient and observer scar assessment scale (POSAS) recently emerged as a promising method, reflecting both observer's and patient's opinions in evaluating scar. This tool was shown to be consistent and reliable in burn scar assessment, but it has not been tested in the setting of skin graft scar in skin cancer patients. OBJECTIVE To evaluate facial skin graft scar applied to PO...