Objective: This study aims to obtain a good activity of radiotheranostic kit for cancer which is built by combining (S)-2-amino-4-(3,5-dichlorophenyl) butanoic acid (ADPB) with various bifunctional chelators.
 Methods: was conducted through in silico method that consists molecular docking simulation using AutoDock 4 as well ADMET prediction vNN-ADMET and Pre-ADMET. Six chelators (i.e. CTPA...

The present study provides an elaborate assessment of the performance of olfactometers in terms of odorant recovery for a selection of odorants emitted from livestock houses. The study includes three different olfactometer dilution systems, which have been in use at accredited odor laboratories. They consist of: (i) a custom-built olfactometer made of glass tubes, (ii) a TO8 olfactometer, and (...

The article describes a two-step synthesis of diastereomeric 3-hydroxy-2-methyl-3-(4-biphenylyl)butanoic acids. In the first step an intermediate alpha-bromo propanoic acid 1-ethoxyethyl ester was synthesized. The second step is a new modified Reformatsky reaction in presence of Zn in tetrahydrofuran (THF) at -5 to 10 degrees C between the previously synthesized intermediate and 4-acetylbipheny...

A vegetarian diet rich in phytochemicals may prevent colon carcinogenesis by affecting biochemical processes in the colonic mucosa. Compounds passing the digestive system reaching the colon could potentially be detected in fecal water. We previously reported that intact fecal water samples from human volunteers significantly decreased prostaglandin production and COX-2 protein expression in col...

The synthesis of the spiro(4,5)decane system is of interest because it constitutes the basic skeleton of the acoranic sesquiterpenes [1]. In this paper we wish to report a stereospecific synthesis of a promising precursor (1) of some of these natural products. According to literature [2] cyclohexanones asubstituted with a co-carboxyalkyl chain yield diketo-spiro systems on treatment with polyph...

Rice sheath blight, a fungal disease caused by Rhizoctonia solani, seriously threatens rice production. Some of the volatile organic compounds (VOCs) produced microbes are inhibitory to growth plant pathogen, and hence may have potential as environmentally friendly antifungal substances. However, information on effect VOCs released rhizosphere bacteria R. solani is scarce. In this study, from c...

The title compound, C12H12FNO3, crystallizes with two independent mol-ecules (A and B) in the asymmetric unit. The dihedral angle between the mean planes of the 3-fluoro-4-methyl-phenyl ring and the oxo-amine group is 25.7 (7)° in mol-ecule A and 71.3 (7)° in mol-ecule B, while the mean plane of the 2-methyl-idene-4-oxo-butanoic acid group is twisted by 76.2 (1)° from that of the oxo-amine grou...

This paper deals with the identification of reaction and mass-transfer rates from concentrations measured in gas-liquid reaction systems. It is assumed that the reactions take place in the liquid bulk only. The identification proceeds in two steps: (i) estimation of the extents of reaction and mass transfer from concentration measurements, and (ii) estimation of the parameters of the individual...