Correction for 'Regioselective C8-metalation of N-phosphine tethered adenine derivatives via C8-H activation' by D. Brackemeyer et al., Dalton Trans., 2017, DOI: 10.1039/c7dt00682a.

Peptides are a class of biomolecules with great potential from the therapeutic point view, because their unique biological properties. Industrially, production stategies adopted produce both target peptide and series impurities that must be removed. Preparative chromatography is technique choice for large-scale purification biomolecules, generally performed in reversed-phase mode, using hydroph...

A two-dimensional gas chromatographic method for the analysis of trace benzene in styrene is described. This method employs the Agilent 6890N GC system equipped with a Deans switch device. The method can be used in a prefractionator mode to analyze trace benzene in styrene according to the proposed ASTM method [1]. It can also be used in a heart-cutting mode to transfer more precisely just the ...

C8-Arylamine-dG and C8-arylamine-dA adducts have been prepared using palladium cross-coupling chemistry. These adducts were subsequently converted into the corresponding 5'-O-DMTr-C8-arylamine-3'-O-phosphoramidites and then used for the automated synthesis of different site-specifically modified oligonucleotides. These "damaged" oligonucleotides have been characterized by ESI-MS, UV thermal sta...

Alpha-ketoglutaric acid (KG) and hydroxymethylfurfural (HMF) are currently being investigated in clinical trials as an approach in targeted cancer therapy. Hence, a method for the simultaneous determination of KG and HMF in plasma has been developed. Due to the strongly discriminative chemical properties of KG and HMF, SPE purification is performed using an ion-exchange cartridge to separate KG...

A simple, selective, rapid, precise and economical reverse phase high -pressure liquid chromatographic method has been developed for the first time for the simultaneous estimation of Taraxerol and Taraxasterol, in natural root and root callus cultures of Taraxacum officinale (TO) , maintained on MS media using hormone combinations , MS+IAA+BA (2ppm+1ppm) and MS+IAA+BA+2,4 D (0.5ppm+1ppm+0.5ppm)...

liquid chromatographic method was developed for the determination of pioglitazone in human plasma. After liquid–liquid extraction with diethylether, samples were quantitated on a NovaPak C8 column using a mixture of acetonitrile–140mM K2HPO4 (40:60, v/v, pH = 4.45) as mobile phase with UV detection at 269 nm. The flow rate was set at 1.4 mL/min. Ethylparaben was used as internal standard and th...

A sensitive liquid chromatographic method for the determination of doxycycline in animal tissues has been prepared and validated. The extraction of the analyte from biological matrix was performed with the solution of oxalic acid and ethyl acetate. The samples were cleaned up by solid phase extraction (SPE) procedure using a carboxylic acid cartridge. Chromatographic separation was carried out ...