The efficiency of four low-cost sorbent materials namely peas husk, broad bean husk, medlar peel and fig leaves, for removing cadmium ions from aqueous solutions, in single systems, has been investigated in batch mode. Kinetic data and equilibrium sorption isotherms were measured. Kinetics of cadmium sorption was contact time, initial cadmium concentration and sorbent type dependent. For a give...

The paper is a review of certain aspects of importance of cadmium and the kidney regarding the assessment of risks and understanding of mechanisms of action. The review discusses the following topics: history and etiology of cadmium-induced kidney dysfunction and related disorders; cadmium metabolism, metallothionein and kidney dysfunction; cadmium in urine as indicator of body burden, exposure...

The insolubilization of cadmium in the soil of a naturally cadmium-contaminated paddy field was studied using an atomized iron powder and an extracting reagent. Cadmium in the soil was extracted into the water phase by calcium chloride. The extracted cadmium was deposited on the iron powder. The deposition of cadmium was significantly influenced by calcium chloride, since the surface area of th...

Cadmium is a potent inhibitor of hepatic microsomal drug biotransformation in the rat. Male rats receiving a single intraperitoneal dose of cadmium exhibit significant decreases in hepatic microsomal metabolism of a variety of substrates. The threshold cadmium dose is 0.84 mg Cd/kg, and the effect lasts at least 28 days. Mechanistically, the inhibitory effect results from decreased cytochrome P...

The high concentrations of cadmium recorded in the digestive gland of cephalopods from various temperate and subpolar waters suggest that these molluscs have developed efficient cadmium detoxification mechanisms. The subcellular distribution of cadmium in the digestive gland cells was investigated in seven cephalopod species from the Bay of Biscay (France) and the Faroe Islands. In most species...

BACKGROUND Exposure to cadmium is associated with human pathologies and altered gene expression. The molecular mechanisms by which cadmium affects transcription remain unclear. It has been proposed that cadmium activates transcription by altering intracellular calcium concentration ([Ca(2+)](i)) and disrupting calcium-mediated intracellular signaling processes. This hypothesis is based on sever...

This study pertains to the role of selenium against the toxic manifestations of chronic cadmium exposure. The kidney is a recognized target organ for chronic cadmium exposure, owing to the very long half-life of cadmium. Cadmium (as cadmium chloride) in a dose of 8 mg kg-1 body wt. was administered orally for a period of 8 weeks in mice. This resulted in a significant decrease in total reduced ...

Twenty-one male rabbits were divided into three groups: rabbits of two groups were given pelleted food containing cadmium chloride at a dose level of 300 micrograms Cd/g over periods of 44 or 19 weeks. Rabbits of the last group were given ordinary commercial pelleted food and served as controls. Cadmium increased urinary protein and amino acid by week 19 and increased it to a remarkably high le...

 Cadmium is more efficiently absorbed from the lungs than the gastrointestinal tract  Cadmium is widely distributed in the body bound mainly to red blood cells. It accumulates in the kidney and liver, where it induces the production of metallothionein that binds approximately 80 90 % of cadmium in the body  There is little or no metabolism of cadmium although it binds to various macromolecul...

†Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577, Japan ‡Division of Advanced Science and Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan §Immunology Frontier Research Center, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan *To whom corre...