BACKGROUND Different antihypertensive drug classes may alter risk for atrial fibrillation. Some studies suggest that drugs that interfere with the renin-angiotensin system may be favorable because of their effect on atrial remodeling. OBJECTIVE To assess and compare the relative risk for incident atrial fibrillation among hypertensive patients who receive antihypertensive drugs from different...

BACKGROUND Although calcium channel blockers are a useful therapy in relieving angina, lowering blood pressure, and slowing conduction of atrial fibrillation, growing evidence has cast doubt on their safety in patients with coronary disease. OBJECTIVE To examine the association between calcium channel blocker therapy at hospital discharge and mortality in a population-based sample of elderly ...

the extracardiac actions of calcium-channel belockers has little been studied.in fact,it has been demonstrated in a number of in viro studies,that calcium-channel belockers are involved in inflammation.here,we evaluated the dose-dependent Effects of verapamil and nifedipine on carrageenan-induced, acute inflammation in the rat paw compared to the anti-inflammatory activites of ibuprofen.the adu...

BACKGROUND Comorbidities of epilepsy comprise some pain disorders, including acute nociceptive pain, therefore, antiepileptic drugs can prove efficacy in the management of this kind of pain albeit with several adverse reactions. The current study aimed to evaluate the modulatory effects of calcium channel blockers on the anticonvulsant and antinociceptive effects of valproic acid (VPA) in penty...

OBJECTIVE To assess short-term and long-term responses to treatment with pulmonary vasodilators in patients with sarcoidosis-related pulmonary hypertension. METHODS A prospective, observational study was performed on eight patients with moderate-to-severe sarcoidosis-related pulmonary hypertension. Patients underwent a short-term vasodilator trial, using inhaled nitric oxide (iNO), IV epopros...