biginelli-type pyrimidines contain an interesting moiety which has attracted considerable attention of medicinal chemists in the last few decades. despite the very diverse pharmacologic effects ascribed to this kind of pyrimidines, there are few reports on the antioxidant evaluation of biginelli pyrimidines. in this study synthesis of some novel biginelli-type pyrimidines is reported. the prepa...

Background and Aim: The aim of this study was to detect the organic compounds of Onopordon leptolepis DC. and also evaluate the anticancer and anti-oxidant effects of the plant extract on CaCO2 cells. Materials and Methods: The effective compounds of air branches of Onopordon leptolepis DC. were studied using phytochemicals methods. Using GC-MS device the components of  ethanolic extract ...

background & aim:oxidative stresses caused by free radicals are known to promote many diseases such as inflammation and cancer; therefore, any plant product that can inhibit free radical production can play an important role in preventing diseases. we aimed to compare the fracture rate and the scavenging activity of free radicals, and the antioxidant composition of rolb-transformed hairy root o...

Plants are one of the natural sources of bioactive molecules with potential abilities against different stress conditions. During pathogenic exposure, an array of biologically active molecules like reactive oxygen intermediates, phytoalexins and defense peptides are synthesized as measure of plant resistance to combat the intensifying conditions. Such molecules play a key role in advancement in...

The objective of this study was to evaluate total phenolic content and antioxidant activity of leaf and different parts of fruit (hull, shell, and kernel) of Bene in Ilam province. Total phenolic content was determined with the Folin- Ciocalteu Reagent (FCR); antioxidant activity of methanolic extracts were examined by DPPH (2,2diphenyl- 1- picrylhydrazyl), FRAP (ferric reducing antioxidant pow...

Leaves of Premna integrifolia belong to Verbanacea is an important rasayana drug in ayurvedic medicine and are considered to be useful in the treatment of variety of ailments. The present study was aimed to assess the for its antioxidant activities. The flavonoid rich fraction, showed antioxidant activity was evaluated using the superoxide scavenging, anti lipid peroxidation, hydroxyl radical s...

Background and objectives: Ferula gummosa Boiss. (Umbelliferae) is a popular medicinal plant, which is known mostly for therapeutic uses of its oleo-gum-resin (Barijeh in Persian). In the present study, the essential oil of F. gummosa roots was investigated for its phytochemical constituents, antioxidant activity and toxicity potential. Method...

Free radicals alter DNA, resulting in various chronic disorders, including cancer. Herbal therapy has a significant potential to block cancer progression and other diseases. The Tamarix aphylla plays an essential role the modulation of free radicals. Calotropis procera (leaves), tropical medicinal plant, shown protective effects against progression. We have examined antioxidant separate or comb...

Gnidia glauca and Dioscorea bulbifera are traditional medicinal plants that can be considered as sources of natural antioxidants. Herein we report the phytochemical analysis and free radical scavenging activity of their sequential extracts. Phenolic and flavonoid content were determined. Scavenging activity was checked against pulse radiolysis generated ABTS(•+) and OH radical, in addition to D...

In the present investigation, the antioxidant activity and free radical scavenging activity of Crambe cordifolia plant were spectrophotometrically studied. Free radical scavenging activity was determined by DPPH method and the obtained IC value was 1106.65 μg/mL. For comparison, the IC value of standard ascorbic acid 50 50 was 21.69 μg/mL. Antioxidant activity was determined by phosphomolybdate...