This investigation evaluates the effect of education about the importance of pap smear test for prevention and early detection of cervical cancer based on the knowledge and practice of girls primary school teachers. The participants in this study were 163 teachers divided in two experimental and control groups. After gathering data of pre- test in both groups, researcher performed an education...

Background: According to some studies in the western countries, %12.7 of total female cancers and %9.8 of all deaths resulted from cancers in the females are due to genital system carcinoma. Methods: The present analytic cross sectional study was done on the cancer registry data of Yazd province for the evaluation of trend of genital carcinoma occurrence amongst females from 2006 to 2010. The t...

Background Cancer of the cervix is a common cause malignancy. Its association with systemic lupus erythematosus (SLE) debatable. Objective Early detection cervical pre-neoplastic lesion in SLE patients. Method A case control study was performed on 64 group and using colposcopy, pap smear histopathological examination. Conclusion This revealed that preneoplastic neoplastic lesions were higher gr...

two set of 2-aryl-5,6-dihydropyrrolo[2,1-a] isoquinolines were designed and synthesized to evaluate their biological activities as topoisomerase inhibitors. cytotoxic activity of the synthesized compounds 4a-e and 7a-d was assessed against several human cancer cell lines, including mcf-7 (breast cancer cell), hepg2 (liver hepatocellular cells), a549 (adenocarcinomic human alveolar basal epithel...

OBJECTIVE The aim of this analysis was to examine the management of cervix cancer in elderly patients referred for radiotherapy and the results of treatment in terms of overall survival (OS), relapse-free survival (RFS), and treatment-related toxicities. METHODS Patients were eligible if they were aged ≥75 years, newly diagnosed with cervix cancer and referred for radiotherapy as part of thei...

Cervical cancer is associated with abnormal expression of multiple genes. Survivin and Bcl-2 proteins are apoptosis inhibitors. The tumor suppressor gene CD82, which encodes the protein KAI1, is downregulated in cervical cancer, and is associated with differentiation degree. We investigated the expression levels of three proteins and their correlation with metastasis in cervical cancer by compa...