Lipocalins are a structurally conserved and diversely functional family of proteins that are of potential importance in epididymis functions. The rat Lcn9 gene was cloned by in silico methods and genome walking based on homology to the rhesus monkey epididymal ESC513 and its polyclonal antisera were prepared. The rat Lcn9 gene is located on chromosome 3p13 spanning 7 exons, contains 2.3 kb and ...

It is well known that transit through the epididymis involves an increase in the compaction of sperm chromatin, which acquires fully condensed status at the caput epididymidis. The purpose of this study was to compare the terminal deoxyribonucleotidyl transferase-mediated dUTP nick end-labelling (TUNEL) assay, the comet assay, the sperm chromatin structure assay (SCSA) and the sperm chromatin d...

AIM To study the secretory activity and androgen regulation of glutathione peroxidase (GPx) in epithelial cell cultures from human epididymis. METHODS Tissue was obtained from patients undergoing therapeutic orchidectomy for prostatic cancer. Epithelial cell cultures were obtained from the caput, corpus and cauda epididymides. Enzymatic activity was measured in conditioned media by colorimetr...

As part of an investigation into the recent epidemic of deaths from asthma in New Zealand, trends in the sales of drugs for asthma in New Zealand, Australia, and the United Kingdom during 1975-81 were examined. Data on sales of drugs were obtained from an international pharmaceutical market research organisation. A striking increase in sales of sympathomimetic aerosols, steroid aerosols, and th...

Biceps brachii is stated as one of the muscles that shows most frequent anatomical variations. Its most commonly reported anomaly is the presence of a third head arising from the humerus which is termed as Caput Accessorium ,therefore, detailed knowledge of this variation in different populations is important for surgical interventions of the arm, nerve compression syndromes and in unexplained ...

prizes for doctors working on immunity were those received in 1960 by Sir Macfarlane Burnet (35) and Sir Peter Medawar for their work in acquired immunological tolerance to tissue transplants. The 1913 medicine prize was awarded to Charles Robert Richet, 1850-1935, the French physiologist, for his work on serology and serum treatment. Together with the French bacteriologist Paul Jones Portier, ...

Androgen is essential for maintenance of spermatogenesis in the testis and for maturation of spermatozoa in the epididymis. The effects of androgen are mediated through its receptor (AR), the levels of which are, in turn, regulated by androgen. Previous studies have shown that AR concentrations in Leydig and Sertoli cells are differentially regulated during development. The aim of the present s...

The mammalian epididymis is the site where spermatozoa are matured and then stored. Though many studies have described epididymal functions and their regulation, little is known about how aging affects this tissue. The Brown Norway rat, which does not show the many age-related pathologies common to other rat strains, was used as a model to study aging of the epididymis. The present study was de...

Zebra mussels (ZMs) (Dreissena polymorpha) and Eurasian watermilfoil (EWM) (Myriophyllum spicatum) are aggressive aquatic invasive species posing a conservation burden on Minnesota. Recognizing areas at high risk for invasion is a prerequisite for the implementation of risk-based prevention and mitigation management strategies. The early detection of invasion has been challenging, due in part t...

Caput succedaneum and cephalohematoma are conditions that rarely evoke much concern in the NICU but deserve more attention. This article examines the two conditions, reviews the literature, discusses possible complications, and leaves the reader with a heightened awareness of these seemingly benign lesions.