نتایج جستجو برای: carbapenem resistant
تعداد نتایج: 194064 فیلتر نتایج به سال:
BACKGROUND Infection with carbapenem-resistant Acinetobacter baumannii has been associated with high morbidity and mortality in solid organ transplant recipients. The main objective of this study was to assess the influence of carbapenem resistance and other potential risk factors on the outcome of A. baumannii infection after kidney and liver transplantation. METHODS Retrospective study of a...
Background: Carbapenem-resistant Acinetobacter baumannii strains are one of the most severe factors in hospital infection worldwide, which beta-lactamase enzyme is main resistance mechanisms. Objectives: This study aimed to evaluate presence carbapenem-resistant genes and determine antibiotic patterns clinical isolates A. from patients hospitalized Shahid Kamyab Hospital, Mashhad, Iran. Methods...
Carbapenems are regularly used as the last choice for the management of multidrug-resistant E. coli and Klebsiella infections3. However, the recent emergence and dissemination of carbapenem resistance raise a question on the effectiveness of empirical therapy with carbapenems4,5. In India, there are no valid data on the prevalence of carbapenem-resistant Enterobacteriaceae (CRE)6; although a fe...
conclusions this study demonstrated the co-existence of rmtc and blandm-1 genes for the first time in turkey. the spread of this resistant type should be monitored and limited through molecular surveillance. results twenty k. pneumoniae strains showed resistance to amikacin, and 40 were resistant to gentamicin. the mic value was found to be > 512 µg/ml in five amikacin-resistant strains and > 1...
Genetic screening of Pseudomonas aeruginosa (PSDA) and Acinetobacter baumannii (ACB) reveals genes that confer increased susceptibility to β-lactams when disrupted, suggesting novel drug targets. One such target is lytic transglycosylase. Bulgecin A (BlgA) is a natural product of Pseudomonas mesoacidophila and a lytic transglycosolase inhibitor that works synergistically with β-lactams targetin...
Carbapenem resistance among Enterobacteriaceae is an emerging problem worldwide. Klebsiella pneumoniae carbapenemase (bla(KPC)) enzymes are among the most common beta-lactamases described. In this study, we report the development and validation of a real-time PCR (q-PCR) assay for the detection of bla(KPC) genes using TaqMan chemistry. The q-PCR amplification of bla(KPC) DNA was linear over 7 l...
5 Abstract Aim: To analyse the occurrence of bla genes (blaIMP, blaVIM, blaGIM, blaSIM, blaSPM, blaPER, blaKPC, and blaOXA) responsible for carbapenemresistance, as well as the presence of cephalosporin-resistance genes (blaCTX-M, blaTEM, blaSHV and blaampC ) by polymerase chain reactions (PCRs). Methods: The study was performed on routine samples subjected to culture and antibiotics susceptibi...
Background. This study described various molecular and epidemiological characters determining antibiotic resistance patterns in Pseudomonas aeruginosa isolates. Methods. A total of 34 carbapenem-resistant P. aeruginosa clinical isolates were isolated from samples collected at a tertiary hospital in Riyadh, Saudi Arabia, from January to December 2011. Susceptibility testing, serotyping, molecula...
OBJECTIVE To identify the risk factors for carbapenem resistant bacteraemia and mortality due to gram negative bacteraemia in a developing country. METHODS A prospective cohort study was conducted at the Sindh Institute of Urology and Transplantation (SIUT) from June to October 2012. Hospitalized patients > 15 years of age with gram negative bacteraemia were included and followed for a period...
Acinetobacter baumannii has become one of the major infection threats in intensive care units (ICUs) globally. Since 2008, A. baumannii has been the leading cause of ventilator-associated pneumonia (VAP) in our ICU at an infectious disease hospital in southern Vietnam. The emergence of this pathogen in our setting is consistent with the persistence of a specific clone exhibiting resistance to c...
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