[reaction: see text] A novel type of photo-protecting group for carbonyl compounds is described. The protecting group is readily accessed in one step from commercially available material. Installation of the protecting group upon the carbonyl compounds is achieved in excellent yields. The carbonyl compounds in their protected form are remarkably stable under various conditions and can be releas...

Hexamethylenetetramine-bromine on wet alumina rapidly regenerates carbonyl compounds from their corresponding semicarbazone using microwave under solventless system.

hexamethylenetetramine-bromine on wet alumina rapidly regenerates carbonyl compounds from their corresponding semicarbazone using microwave under solventless system.

Carbonyl containing xenobiotics may be susceptible to NADPH-dependent cytochrome P450 (P450) and carbonyl-reduction reactions. In vitro hepatic microsome assays are routinely supplied NADPH either by direct addition of NADPH or via an NADPH-regenerating system (NRS). In contrast to oxidative P450 transformations, which occur on the periphery of a microsome vesicle, intraluminal carbonyl reducti...

Therapeutic induction of apoptosis is an important goal of anticancer drug design. Cellular carbonyl stress mediated by endogenous reactive carbonyl species (RCS) such as glyoxal and methylglyoxal (MG) affects proliferative signaling and metastasis of human tumor cells. Recent research suggests that RCS produced constitutively during increased tumor cell glycolysis may be antiapoptotic survival...

The title compound, C5H3N3OS, is almost planar (r.m.s. deviation for the ten non-H atoms = 0.018 Å) and forms an extended layer structure in the (100) plane, held together via hydrogen-bonding inter-actions between adjacent mol-ecules. Of particular note is the occurrence of RC-H⋯N(-)=N(+)=NR inter-actions between an aromatic C-H group and an azide moiety which, in conjunction with a complement...

Aromatic carbonyl compounds in combination with B(C(6)F(5))(3) are able to activate H(2) heterolytically. The reactivity of the carbonyl-B(C(6)F(5))(3) adduct is initiated by its thermal dissociation into components. After H(2) addition, aromatic carbonyl compounds convert into aryl-substituted methanes or alcohols.

It was found that cesium carbonate has a unique catalytic ability on the reaction of carbonyl compounds with diphenyl diselenide to give the corresponding alpha-phenylseleno carbonyl compounds in moderate to good yields. Similarly, the alpha-phenylthiolation of carbonyl compounds with diphenyl disulfide was promoted by the cesium carbonate catalyst.

Trinuclear cyclopentadienylniobium carbonyls are of interest since Cp3Nb3(CO)7 (Cp=eta5-C5H5) is a stable molecule having a unique face-bridging carbonyl group formally donating six electrons to the Nb3 triangle through one Nb-C sigma-bond and two orthogonal pi-bonds. In this connection, the molecules Cp3Nb3(CO)n (n=9, 8, 7, 6) have been examined by density functional theory. The saturated deri...

Carbon-carbon bond cleavage/functionalization is synthetically valuable, and selective carbonyl-C(sp3 ) bond cleavage/alkynylation presents a new perspective in constructing ynamides, ynoates, and ynones. Reported here is the first alkoxyl-radical-enabled carbonyl-C(sp3 ) bond cleavage/alkynylation reaction by photoredox catalysis. The use of novel cyclic iodine(III) reagents are essential for ...