Cassava tubers suffer from postharvest physiological deterioration (PPD) which normally sets in within 72 hours of harvest. This study examines the role scopoletin and carotenoids onset or delay PPD two transgenic varieties EC20-7 EC20-8 compared to a wild variety TME-7. Scopoletin were quantified by liquid chromatography-mass spectrometry. The content (0.10 – 0.20 nmol/g) fresh was n...

Muscle atrophy increases the production of reactive oxygen species and the expression of atrophy-related genes, which are involved in the ubiquitin–proteasome system. In the present study, we investigated the effects of b-carotene on oxidative stress (100mM-H2O2)-induced muscle atrophy in murine C2C12 myotubes. b-Carotene (10mM) restored the H2O2-induced decreased levels of myosin heavy chain a...

Red palm oil (RPO) contains high concentrations of beta- and alpha-carotene, and is presumed to possess a higher vitamin A value than other foods. The objective was to determine the metabolic vitamin A and carotene values of refined red palm oil in healthy adult subjects, using a stable isotope reference method. Twelve healthy subjects were administered a small standardised meal containing 10 g...

The modulating effect of the combined dietary feeding of beta-carotene and perilla oil, which is rich in alpha-linolenic acid, on the development of azoxymethane (AOM)-induced colonic aberrant crypt foci (ACF) was investigated in male F344 rats. Rats received oral administration of beta-carotene (0, 50 or 200 mg/kg body weight/day) and fed a basal diet containing either 12% olive oil, 3% perill...

Oral submucous fibrosis (OSMF) is a chronic, insidious and disabling condition affecting the oral cavity, being especially prevalent in India and South East Asia. However, considering its high prevalence and potential to undergo malignant transformation, OSMF has not been widely investigated with respect to levels of antioxidants, especially beta carotene. In the present study, an attempt was m...

1. Examination of two zooplankton species predominating in fish ponds, Daphnia magna and Chironomus larvae, revealed the presence of alpha- and beta-carotene, echinenone, canthaxanthin and 3-hydroxy-4-oxo-beta-carotene in Daphnia, and beta-carotene and cryptoxanthin ester in Chironomus. No specific provitamins A(2) (containing a 3,4-dehydro-beta-ionone ring) were detected. 2. Guppies (Lebistes ...

Findings from several β-carotene supplementation trials were unexpected and conflicted with most observational studies. Carotenoids other than β-carotene are found in a variety of fruits and vegetables and may play a role in this important malignancy, but previous findings regarding the five major carotenoids are inconsistent. The authors analyzed the associations between dietary β-carotene, β-...

Vascular complications such as atherosclerosis hinder the treatment of diabetes. We hypothesized that moderate supplementation with b-carotene might help prevent diabetic vascular complications through its impact on lipid metabolism. Forty Sprague-Dawley rats were fed AIN-76 control diet, or the same diet supplemented with b-carotene (7.2 mg/kg diet) for 3 weeks, then diabetes was induced in ha...

Dr. James Allen Olson helped us to define the role of beta-carotene in human health by categorizing these as “functions, actions and associations.” In the last decade, significant research has shown that betacarotene acts as an antioxidant in biologically relevant systems, affects several aspects of human immune function and higher intake/serum levels are associated with improvements in certain...

-carotene has been used for years as natural food colorants and in cosmetics and healthcare due to their antioxidant property. The production of -carotene by Mucor azygosporus was evaluated, utilizing deproteinized waste whey filtrate. Since pigments are intracellular, their extraction needed after cell cultivation. In this study, different strategies for extraction of -carotene from M. azyg...