Liver involvement in patients with sickle cell anemia/trait includes a wide range of alterations, from mild liver function test abnormalities to cirrhosis and acute liver failure. Approximately 15-30% of patients with sickle cell anemia present cirrhosis at autopsy. The pathogenesis of cirrhosis is usually related to chronic hepatitis B or C infection or to iron overload resulting from the many...

Bleeding in patients with liver cirrhosis is primarily caused by gastroesophageal varix in association with extensive collateral circulation, portal hypertensive gastropathy, a Mallory-Weiss tear and peptic ulcer disease. The spontaneous rupture of an artery, as a result of coagulopathy, is extremely rare in patients with liver cirrhosis; however, we recently observed a case of a spontaneous ru...

Patients with decompensated hepatic cirrhosis may present systemic alterations and dysfunction of multiple organs. Ascites, portal hypertension, esophageal varices, encephalopathy are common complications arising from cirrhosis. The aim this paper is to report a case patient liver the transjugular intrahepatic portosystemic shunt. Male, elderly, ex-alcoholic, diagnosed cirrhosis, ascites, varic...

introduction: indian childhood cirrhosis is a chronic liver disease usually seen in paediatric age group and is unique to the indian subcontinent. the definitive causative factor for the disease is not found till now but excess copper ingestion has been associated with it.case presentation: an indian origin one and half year old premorbidly normal male child presented with history of gradual di...

We present a case of a 50-year-old man with advanced liver cirrhosis and native valve infective endocarditis caused by methicillin-resistant Staphylococcus epidermidis. Bacterial infections are one of the most common complications of liver cirrhosis, but reports of infective endocarditis in patients with liver cirrhosis are relatively rare. Because of vulnerability of patients with advanced cir...

Experimental models for hepatic lesions are necessary so the effectiveness of new drugs in reversing cirrhosis or fibrosis can be tested. This is the case of liver cirrhosis, which requires animal models. Three drugs widely used to induce cirrhosis in animal models are carbon tetrachloride (CCI4), Dimethylnitrosamine (DMN), and Thioacetamide (TAA). TAA has been largely used, but a model that co...

OBJECTIVE To identify the limitations in palliative care provision in the last year of life for people with liver cirrhosis and potential barriers to and enablers of palliative care. DESIGN Mixed methods, including a retrospective case note review, qualitative focus groups and individual interviews. SETTING A tertiary referral liver centre in the south of England (UK). PARTICIPANTS Purpos...

Nonalcoholic fatty liver disease (NAFLD) is a fatty liver disease occurring in patients without alcohol consumption. It includes a broad spectrum of liver disease, from fatty infiltration, inflammation and fibrosis, to cirrhosis, usually having obesity, hyperlipidemia, and diabetes mellitus as its etiology. NAFLD-related cirrhosis has rarely been reported in Taiwan. We herein report a 41-year-o...

A variety of pathologic changes may be associated with Banti's syndrome. These may include cirrhosis of the liver, splenic vein thrombosis, cavernomatous transformation of the portal vein and aneurysm of the splenic artery. However, a protracted search of the literature revealed no case of fusiform aneurysm of the portal vein as a result of an enlarged, congested spleen and liver cirrhosis. As ...