Safety pharmacology studies help in identifying preclinical adverse drug reactions. We carried out routine safety pharmacology with focus on cardiovascular variables and pharmacokinetic herb-drug interaction studies on rats fed with standardized traditional hydro-alcoholic extract and technology-based supercritical extract of Cassia auriculata for 12 weeks. Our studies indicate that both these ...

Medicinal plants are source of important therapeutic aids for alleviating human ailments. The history of drug is intricately interowen with natural products for centuties. In tune with this effort, the objective set for the present investigation is to estimate the phenolic and flavonoid contents in flower extracts of Cassia auriculata and Cassia siamea. The preliminary qualitative screening rev...

BACKGROUND The herbal formulation consisting of Andrographis paniculata Nees., Cassia fistula L., Foeniculum vulgare Mill. and Cuminum cyminum L. is widely used by the local traditional practitioners in rural Northern Karnataka for spasmodic abdominal pain. OBJECTIVE The present study was undertaken to evaluate safety and spasmolytic effect of poly-herbal formulation. MATERIALS AND METHODS ...

Various extracts of flowers of Cassia fistula Linn (Leguminosae) such as petroleum ether (60-80°), chloroform, acetone, ethanol, aqueous, and crude aqueous extracts and two fractions of ethanol extract were tested for antihyperglycemic activity in glucose-overloaded hyperglycemic rats. The effective antihyperglycemic extracts and fraction were tested for their hypoglycemic activity at two dose ...

Endophytic fungi are present within all plants and more than one million species predicted to be present. They widely studied as they promote plant growth well resistance environmental stress, produce bioactive compounds that have industrial applications play a vital role in biogeochemical cycles. The medicinal Cassia (commonly known seenas) belongs the Order Fabales Family Caesalpiniaceae. Thi...

Tropical plants are utilized in traditional medicine and are a storehouse of secondary metabolites, some of which display medicinal properties. Five plants were selected for investigation, namely Cassia fistula, Delonix regia, Senna siamea, Spathodea campanulata and Tibouchina granulosa. Extracts of the inflorescence of these plants were prepared and their antioxidant, total phenolics and fatty...

Background: Colitis is an inflammatory bowel disease, which is treated effectively with antioxidant and anti-inflammatory drugs. This study evaluated the anti-inflammatory effects of the extracts of Viola odorata and Cassia fistula on the acetic acid-induced colitis in rats. Methods: We determined the total contents of phenols, alkaloids, saponins, and tannins in the plants’ extracts. Further...

The fumigant, contact, and repellent activities of four essential oils extracted from Citrus limonum (Sapindales: Rutaceae), Litsea cubeba (Laurales: Lauraceae), Cinnamomum cassia, and Allium sativum L. (Asparagales: Alliaceae) against 6th instars and adults of the darkling beetle, Alphitobius diaperinus (Panzer) (Coleoptera: Tenebrionidae), one of the main pests of materials and products of Ju...